Interventions for dialysis patients with hepatitis C virus (HCV) infection

• Published in: Cochrane database of systematic reviews no. 8; p. CD007003
• Main Authors: Prabhu, Ravindra A, Nair, Sreekumar, Pai, Ganesh, Reddy, Nageswara P, Suvarna, Deepak
• Format: Journal Article
• Language: English
• Published: England 19.08.2015
• Subjects: Antiviral Agents - therapeutic use; Drug Therapy, Combination; Hepatitis C - complications; Hepatitis C - drug therapy; Hepatitis C - mortality; Humans; Interferon alpha-2; Interferon-alpha - therapeutic use; Interferons - therapeutic use; Polyethylene Glycols - therapeutic use; Randomized Controlled Trials as Topic; Recombinant Proteins - therapeutic use; Recurrence; Renal Dialysis - methods; Renal Insufficiency, Chronic - complications; Renal Insufficiency, Chronic - mortality; Renal Insufficiency, Chronic - therapy; Ribavirin - therapeutic use; Withholding Treatment - statistics & numerical data

Hepatitis C virus (HCV) infection is common in chronic kidney disease (CKD) patients on dialysis, causes chronic liver disease, increases mortality and impacts kidney transplant outcomes. Sustained response to the preferred treatment with standard or pegylated (PEG) interferon is seen in 39% with si...