Single QTL mapping and nucleotide-level resolution of a physiologic trait in wine Saccharomyces cerevisiae strains

• Published in: FEMS yeast research Vol. 7; no. 6; pp. 941 - 952
• Main Authors: Marullo, Philippe, Aigle, Michel, Bely, Marina, Masneuf-Pomarède, Isabelle, Durrens, Pascal, Dubourdieu, Denis, Yvert, Gaël
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.09.2007; Oxford University Press; Oxford University Press (OUP)
• Subjects: Acetic acid; Acetic Acid - metabolism; Acid production; Aneuploidy; ASP1; Asparaginase; Asparaginase - metabolism; Asparagine; Carbon dioxide; Carbon Dioxide - metabolism; Chromosome Mapping; Chromosomes, Fungal - genetics; DNA microarray; DNA microarrays; Fermentation; Gene mapping; Genetic crosses; Genetic diversity; Genetics; Genome, Fungal - genetics; Hybridization; Life Sciences; Musts; Nitrogen - metabolism; Oligonucleotides; Phenotype; Phenotypes; Phenotypic variations; Polymorphism, Single Nucleotide - genetics; Pyrophosphatases - genetics; Pyrophosphatases - metabolism; QTL mapping; Quantitative genetics; Quantitative Trait Loci; Reproducibility of Results; Saccharomyces cerevisiae; Saccharomyces cerevisiae - classification; Saccharomyces cerevisiae - genetics; Saccharomyces cerevisiae Proteins - genetics; Saccharomyces cerevisiae Proteins - metabolism; Single-nucleotide polymorphism; Strains (organisms); Wine; Wine - microbiology; wine fermentation; Yeast; DNA microarray; aneuploidy; wine fermentation; acetic acid; QTL mapping; ASP1

Abstract Natural Saccharomyces cerevisiae yeast strains exhibit very large genotypic and phenotypic diversity. However, the link between phenotype variation and genetic determinism is still difficult to identify, especially in wild populations. Using genome hybridization on DNA microarrays, it is no...