Novel immune-type receptor genes

• Published in: Immunological reviews Vol. 181; no. 1; pp. 250 - 259
• Main Authors: Litman, Gary W., Hawke, Noel A., Yoder, Jeffrey A.
• Format: Journal Article
• Language: English
• Published: Copenhagen Munksgaard International Publishers 01.06.2001; Blackwell
• Subjects: Animals; Biological and medical sciences; Biological Evolution; Fishes - genetics; Fishes - immunology; Fundamental and applied biological sciences. Psychology; Fundamental immunology; General aspects; Genetic Variation; Genome; Immunopathology; Medical sciences; Models, Biological; Molecular Structure; Polymerase Chain Reaction; Receptors, Immunologic - chemistry; Receptors, Immunologic - genetics; Sphoeroides nephelus; Human; Gene; Molecular structure; Multigene family; Review; Novel immune-type receptor gene; Genome; Biological receptor

Novel immune‐type receptor (NITR) genes, which initially were identified in the Southern pufferfish (Spheroides nephelus), encode products which consist of an extracellular variable (V) and V‐like C2 (V/C2) domain, a transmembrane region, and a cytoplasmic tail, which typically possesses an immunore...