Robust Bayesian methods for monitoring clinical trials

• Published in: Statistics in medicine Vol. 14; no. 12; p. 1379
• Main Authors: Greenhouse, J B, Wasserman, L
• Format: Journal Article
• Language: English
• Published: England 30.06.1995
• Subjects: Bayes Theorem; Clinical Trials as Topic - statistics & numerical data; Data Collection; Data Interpretation, Statistical; Extracorporeal Membrane Oxygenation - statistics & numerical data; Fluorouracil - administration & dosage; Fluorouracil - adverse effects; Granulocyte Colony-Stimulating Factor - administration & dosage; Humans; Infant, Newborn; Leucovorin - administration & dosage; Leucovorin - adverse effects; Leukopenia - chemically induced; Leukopenia - prevention & control; Likelihood Functions; Neoplasms - drug therapy; Persistent Fetal Circulation Syndrome - mortality; Persistent Fetal Circulation Syndrome - therapy; Stomatitis - chemically induced; Stomatitis - prevention & control; Survival Rate; Treatment Outcome

Bayesian methods for the analysis of clinical trials data have received increasing attention recently as they offer an approach for dealing with difficult problems that arise in practice. A major criticism of the Bayesian approach, however, has focused on the need to specify a single, often subjecti...