Diffusion MRI: apparent diffusion coefficient (ADC) values in the normal brain and a classification of brain disorders based on ADC values

• Published in: Computerized medical imaging and graphics Vol. 25; no. 4; pp. 299 - 326
• Main Author: Sener, R.N.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Ltd 01.07.2001; Elsevier Science
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Apparent diffusion coefficient; Biological and medical sciences; Body Water - diagnostic imaging; Brain; Brain Diseases - classification; Brain Diseases - diagnostic imaging; Brain Diseases - pathology; Case-Control Studies; Child; Child, Preschool; Classification of brain disorders, diffusion MRI; Diffusion; Diffusion-weighted MR imaging; Female; Humans; Image analysis; Infant; Infant, Newborn; Investigative techniques, diagnostic techniques (general aspects); Magnetic Resonance Imaging - methods; Male; Medical imaging; Medical sciences; Middle Aged; Nervous system; Nervous system involvement in other diseases. Miscellaneous; Neurology; Neurophysiology; Normal brain, diffusion MRI; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Radionuclide Imaging; Reference Values; Tissue; Classification of brain disorders, diffusion MRI; Normal brain, diffusion MRI; Diffusion-weighted MR imaging; Apparent diffusion coefficient; Human; Evaluation; Nervous system diseases; Artefact; Nuclear magnetic resonance imaging; White matter; Cerebral disorder; Weighting; Central nervous system disease; Classification; Technique; Diagnostic aid; Diffusion coefficient; Medical application

Diffusion-weighted imaging, dependent on motion of water molecules, provides information regarding tissue integrity. Apparent diffusion coefficient (ADC) values in the normal brain parenchyma, and those in a variety of lesions were studied by echo-planar diffusion MRI in 310 cases. Brain disorders w...