Mean platelet volume as an indicator of platelet activation: methodological issues

• Published in: Platelets (Edinburgh) Vol. 13; no. 5-6; pp. 301 - 306
• Main Authors: Park, Yongsoon, Schoene, Norberta, Harris, William
• Format: Journal Article
• Language: English
• Published: England Informa UK Ltd 2002; Taylor & Francis
• Subjects: Adult; Blood Platelets - cytology; Blood Platelets - physiology; Cell Size; Collagen - pharmacology; Fasting; Female; Humans; Hypertriglyceridemia - blood; Male; Middle Aged; Plant Oils - administration & dosage; Plant Oils - pharmacology; Platelet Activation; Platelet Function Tests - methods; Temperature

Background: Mean platelet volume (MPV) is increased in patients at high risk for athero-thrombotic diseases. Thus, an elevated MPV may be a risk marker for platelet activation. Methods: Healthy subjects with normal triglyceride (TG) levels (90 - 6 mg/dl; n = 40) or mild hypertriglyceridemia (161 - 7...