Early Response Roles for Prolactin Cortisol and Circulating and Cellular Levels of Heat Shock Proteins 72 and 90α in Severe Sepsis and SIRS

• Published in: BioMed research international Vol. 2014; no. 2014; pp. 1 - 8
• Main Authors: Nanas, S., Briassoulis, George, Routsi, C., Tsagarakis, S., Botoula, E., Psarra, K., Goukos, D., Briassouli, Efrossini, Apostolou, Kleovoulos, Vardas, K., Magira, E.
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 01.01.2014
• Subjects: Adrenocorticotropic Hormone - blood; Adult; Case-Control Studies; Female; HSP72 Heat-Shock Proteins - blood; HSP90 Heat-Shock Proteins - blood; Humans; Hydrocortisone - blood; Male; Middle Aged; Prolactin - blood; Sepsis - blood; Sepsis - epidemiology; Stress, Physiological; Systemic Inflammatory Response Syndrome - blood; Systemic Inflammatory Response Syndrome - epidemiology

Objective. To evaluate the early heat shock protein (HSP) and hormonal stress response of intensive care unit (ICU) patients with severe sepsis/septic shock (SS) or systemic inflammatory response syndrome (SIRS) compared to healthy subjects (H). Methods. Patients with early (first 48 hrs) SS ( n = 2...