The cis Element and Factors Required for Condensin Recruitment to Chromosomes

• Published in: Molecular cell Vol. 34; no. 1; pp. 26 - 35
• Main Authors: Johzuka, Katsuki, Horiuchi, Takashi
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 10.04.2009
• Subjects: Adenosine Triphosphatases - metabolism; Carrier Proteins - genetics; Cell Cycle Proteins - genetics; Cell Cycle Proteins - metabolism; Cell Cycle Proteins - physiology; CELLCYCLE; Chromosomes, Fungal - metabolism; DNA; DNA Replication - physiology; DNA, Ribosomal - metabolism; DNA-Binding Proteins - metabolism; DNA-Binding Proteins - physiology; Intracellular Signaling Peptides and Proteins; Multiprotein Complexes - metabolism; Mutation; Nuclear Proteins - genetics; Nuclear Proteins - metabolism; Nuclear Proteins - physiology; Repetitive Sequences, Nucleic Acid; Saccharomyces cerevisiae - genetics; Saccharomyces cerevisiae - metabolism; Saccharomyces cerevisiae Proteins - genetics; Saccharomyces cerevisiae Proteins - metabolism; Saccharomyces cerevisiae Proteins - physiology; CELLCYCLE; DNA

Condensins are required for segregation of rDNA repeats in concert with Fob1, a replication fork block protein binding at the replication fork barrier (RFB) site within rDNA in yeast. Here, we found that the RFB site functions as a cis element for Fob1-dependent condensin recruitment onto chromosome...