Scopolamine disrupts place navigation in rats and humans: a translational validation of the Hidden Goal Task in the Morris water maze and a real maze for humans - Laczó, Jan; Markova, Hana; Lobellova, Veronika; Gazova, Ivana; Parizkova, Martina; Cerman, Jiri; Nekovarova, Tereza; Vales, Karel; Klovrzova, Sylva; Harrison, John; Windisch, Manfred; Vlcek, Kamil; et al. (Psychopharmacology, 2017)
Keywords: Adult; Alzheimer's disease; Analysis; Animals; Anti-Alzheimer's disease agents; Biomedical and Life Sciences; Biomedicine; Cholinesterase Inhibitors - pharmacology; Cognition & reasoning; Donepezil; Dosage and administration; Double-Blind Method; Female; Humans; Indans - pharmacology; Male; Maze Learning - drug effects; Muscarinic Antagonists - pharmacology; Navigation; Neurosciences; Original Investigation; Pharmacological research; Pharmacology/Toxicology; Physiological aspects; Piperidines - pharmacology; Psychiatry; Psychopharmacology; Rats; Rats, Wistar; Scopolamine; Scopolamine - pharmacology; Spatial ability; Spatial Navigation - drug effects; Studies; Young Adult; Human; Spatial orientation; Acetylcholinesterase inhibitor; Scopolamine; Rat