A microfluidic optical platform for real-time monitoring of pH and oxygen in microfluidic bioreactors and organ-on-chip devices

• Published in: Biomicrofluidics Vol. 10; no. 4; pp. 044111 - 44124
• Main Authors: Mousavi Shaegh, Seyed Ali, De Ferrari, Fabio, Zhang, Yu Shrike, Nabavinia, Mahboubeh, Binth Mohammad, Niema, Ryan, John, Pourmand, Adel, Laukaitis, Eleanor, Banan Sadeghian, Ramin, Nadhman, Akhtar, Shin, Su Ryon, Nezhad, Amir Sanati, Khademhosseini, Ali, Dokmeci, Mehmet Remzi
• Format: Journal Article
• Language: English
• Published: United States American Institute of Physics 01.07.2016; AIP Publishing LLC
• Subjects: Bioreactors; Construction costs; Design modifications; Detection; Electro-optics; Fibroblasts; Low cost; Luminous intensity; Monitoring; Optical communication; Organic light emitting diodes; Oxygen; Photodiodes; Regular; Sensors

There is a growing interest to develop microfluidic bioreactors and organ-on-chip platforms with integrated sensors to monitor their physicochemical properties and to maintain a well-controlled microenvironment for cultured organoids. Conventional sensing devices cannot be easily integrated with mic...