FluBlok, a next generation influenza vaccine manufactured in insect cells

• Published in: Biologicals Vol. 37; no. 3; pp. 182 - 189
• Main Authors: Cox, Manon M.J., Hollister, Jason R.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.06.2009
• Subjects: Animals; Baculovirus; Cell substrate; Hemagglutinin; Influenza vaccine; Influenza Vaccines - genetics; Insect cells; Insecta - genetics; Vaccines, Synthetic - genetics; Cell substrate; Baculovirus; Hemagglutinin; Influenza vaccine; Insect cells

FluBlok, a recombinant trivalent hemagglutinin (rHA) vaccine produced in insect cell culture using the baculovirus expression system, provides an attractive alternative to the current egg-based trivalent inactivated influenza vaccine (TIV). Its manufacturing process presents the possibility for safe...