Imprinting of the Y Chromosome Influences Dosage Compensation in roX1 roX2 Drosophila melanogaster

• Published in: Genetics (Austin) Vol. 183; no. 3; pp. 811 - 820
• Main Authors: Menon, Debashish U, Meller, Victoria H
• Format: Journal Article
• Language: English
• Published: United States Genetics Soc America 01.11.2009; Genetics Society of America
• Subjects: Animals; Chromatin; chromosome transmission; Chromosomes; Compensation; dosage compensation; Dosage Compensation, Genetic; Drosophila melanogaster; Drosophila melanogaster - genetics; Drosophila melanogaster - growth & development; Drosophila melanogaster - metabolism; Drosophila Proteins; Drosophila Proteins - genetics; Drosophila Proteins - metabolism; Female; gene dosage; Gene expression; Gene Expression Regulation, Developmental; Genetics; Genomic Imprinting; growth & development; Immunohistochemistry; Insects; Investigations; Larva; Larva - genetics; Larva - growth & development; Larva - metabolism; Male; males; metabolism; Models, Genetic; mutants; Mutation; Nuclear Proteins; Nuclear Proteins - genetics; Nuclear Proteins - metabolism; phenotype; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA-Binding Proteins; RNA-Binding Proteins - genetics; RNA-Binding Proteins - metabolism; roX1 gene; roX2 gene; Transcription Factors; Transcription Factors - genetics; Transcription Factors - metabolism; X Chromosome; X Chromosome - genetics; Y chromosome; Y Chromosome - genetics

Drosophila melanogaster males have a well-characterized regulatory system that increases X-linked gene expression. This essential process restores the balance between X-linked and autosomal gene products in males. A complex composed of the male-specific lethal (MSL) proteins and RNA is recruited to...