Role of STAT3 in skin fibrosis and transforming growth factor beta signalling - Pedroza, Mesias; To, Sarah; Assassi, Shervin; Wu, Minghua; Tweardy, David; Agarwal, Sandeep K (Rheumatology (Oxford, England), 2018)
Keywords: Animal models; Animals; Autoimmune diseases; Basic and Translational Science; Biopsy; Bleomycin; Collagen; Female; Fibroblasts; Fibrosis; Gene expression; Humans; Interleukin 6; Mice; Mice, Inbred C57BL; Naphthols - pharmacology; Phenotypes; Rodents; Scleroderma; Scleroderma, Systemic - drug therapy; Scleroderma, Systemic - pathology; Signal Transduction - drug effects; Skin - drug effects; Skin - pathology; Skin Diseases - drug therapy; Skin Diseases - metabolism; Skin Diseases - pathology; Smad3 protein; Stat3 protein; STAT3 Transcription Factor - antagonists & inhibitors; STAT3 Transcription Factor - physiology; Sulfonamides - pharmacology; Systemic sclerosis; Therapeutic applications; Transforming Growth Factor beta - physiology; Transforming growth factor-b; fibrosis; systemic sclerosis; STAT3