SIRT3 mediates the effects of PCSK9 inhibitors on inflammation, autophagy, and oxidative stress in endothelial cells - D'Onofrio, Nunzia; Prattichizzo, Francesco; Marfella, Raffaele; Sardu, Celestino; Martino, Elisa; Scisciola, Lucia; Marfella, Lorenza; Grotta, Rosalba La; Frigé, Chiara; Paolisso, Giuseppe; Ceriello, Antonio; Balestrieri, Maria Luisa (Theranostics, 2023)
Keywords: Antibodies; Autophagy; Autophagy - drug effects; Biotechnology; Cardiovascular Diseases; Cholesterol; Cytokines; Endothelial Cells - metabolism; Humans; Inflammation; Inflammation - metabolism; Interleukin-6 - metabolism; Low density lipoprotein; Membranes; Monoclonal antibodies; Oxidative stress; Oxidative Stress - drug effects; PCSK9 Inhibitors - pharmacology; PCSK9 Inhibitors - therapeutic use; Proprotein Convertase 9 - metabolism; Proteins; Research Paper; Sirtuin 3 - metabolism; Software; Tumor necrosis factor-TNF; United Kingdom--UK; United States--US; LDL-cholesterol; endothelial cells; autophagy; inflammation; inflammasome; ROS; PCSK9; cardiovascular diseases; IL-6; oxidative stress; SIRT3