OGA activated glycopeptide-based nano-activator to activate PKM2 tetramerization for switching catabolic pathways and sensitizing chemotherapy resistance - Hou, Da-Yong; Xiao, Wu-Yi; Wang, Jia-Qi; Yaseen, Muhammad; Wang, Zhi-Jia; Fei, Yue; Wang, Man-Di; Wang, Lu; Wang, Hui; Shi, Xinghua; Cai, Meng-meng; Feng, Hai-Tao; et al. (Biomaterials, 2022)
Keywords: biocompatible materials; Breast Neoplasms - drug therapy; Breast Neoplasms - metabolism; breasts; cell proliferation; drug therapy; glucose; Glycolysis; Glycopeptide; glycopeptides; Glycopeptides - metabolism; Humans; Male; metabolites; metastasis; muscles; Muscles - metabolism; Nano-activator; PKM2; Protein Isoforms - metabolism; pyruvate kinase; Pyruvate Kinase - metabolism; serine; Switching catabolic pathways; Glycolysis; Nano-activator; Glycopeptide; PKM2; Switching catabolic pathways