Reduced Diversity and Imbalance of Fecal Microbiota in Patients with Ulcerative Colitis

• Published in: Digestive diseases and sciences Vol. 57; no. 11; pp. 2955 - 2964
• Main Authors: Nemoto, Hideyuki, Kataoka, Keiko, Ishikawa, Hideki, Ikata, Kazue, Arimochi, Hideki, Iwasaki, Teruaki, Ohnishi, Yoshinari, Kuwahara, Tomomi, Yasutomo, Koji
• Format: Journal Article
• Language: English
• Published: Boston Springer US 01.11.2012; Springer; Springer Nature B.V
• Subjects: Adult; Aged; Bacteria; Bacteria - isolation & purification; Bacteroides; Biochemistry; Case-Control Studies; Clostridium; Colitis, Ulcerative - microbiology; Comparative analysis; DNA, Bacterial - analysis; Enterococcus; Feces - microbiology; Female; Gastroenterology; Hepatology; Humans; Intestinal Mucosa - microbiology; Male; Medicine; Medicine & Public Health; Metronidazole; Microbiota (Symbiotic organisms); Middle Aged; Oncology; Organic acids; Original Article; Polymorphism, Restriction Fragment Length; Real-Time Polymerase Chain Reaction; Statistics, Nonparametric; Transplant Surgery; Ulcerative colitis; Fecal microbiota; Organic acids; Diversity; Ulcerative colitis

Background Clinical observations and experimental colitis models have indicated the importance of intestinal bacteria in the etiology of ulcerative colitis (UC), but a causative bacterial agent has not been identified. Aim To determine how intestinal bacteria are associated with UC, fecal microbiota...