An Automatic Platform Based on Nanostructured Microfluidic Chip for Isolating and Identification of Circulating Tumor Cells

• Published in: Micromachines (Basel) Vol. 12; no. 5; p. 473
• Main Authors: Jou, Hei-Jen, Chou, Li-Yun, Chang, Wen-Chun, Ho, Hsin-Cheng, Zhang, Wan-Ting, Ling, Pei-Ying, Tsai, Ko-Hsin, Chen, Szu-Hua, Chen, Tze-Ho, Lo, Pei-Hsuan, Chen, Ming, Hsu, Heng-Tung
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 21.04.2021; MDPI
• Subjects: Antibodies; Automation; Biomarkers; Biopsy; Cancer; CD13; circulating tumor cells; Efficiency; epithelial ovarian cancer; liquid biopsy; Metastasis; Microfluidics; Ovarian cancer; Polyethylene glycol; Sensitivity; SKOV3; Tumors; United States > US; Taiwan; SKOV3; epithelial ovarian cancer; CD13; circulating tumor cells; liquid biopsy

Circulating tumor cell (CTC) test is currently used as a biomarker in cancer treatment. Unfortunately, the poor reproducibility and limited sensitivity with the CTC detection have limited its potential impact on clinical application. A reliable automated CTC detection system is therefore needed. We...