Casting a wide net: use of diverse model organisms to advance toxicology

• Published in: Disease models & mechanisms Vol. 13; no. 4
• Main Authors: Hahn, Mark E., Sadler, Kirsten C.
• Format: Journal Article
• Language: English
• Published: England The Company of Biologists Ltd 01.04.2020; The Company of Biologists
• Subjects: animal models; Animals; Biology; Disease; Enzymes; Evolution; Genomes; Health; Humans; Mammals; Metabolism; Models, Animal; Models, Biological; Organic chemicals; Organisms; PCB; Pesticides; Physiology; Pollutants; Polychlorinated biphenyls; toxicants; Toxicity; Toxicity Tests; Toxicology; Zebra; Zebrafish; Zebrafish; Animal models; Toxicology; Toxicants

Toxicology – the study of how chemicals interact with biological systems – has clear relevance to human health and disease. Persistent exposure to natural and synthetic chemicals is an unavoidable part of living on our planet; yet, we understand very little about the effects of exposure to the vast...