Frondanol, a Nutraceutical Extract from Cucumaria frondosa, Attenuates Colonic Inflammation in a DSS-Induced Colitis Model in Mice - Subramanya, Sandeep B.; Chandran, Sanjana; Almarzooqi, Saeeda; Raj, Vishnu; Al Zahmi, Aisha Salem; Al Katheeri, Radeya Ahmed; Al Zadjali, Samira Ali; Collin, Peter D.; Adrian, Thomas E. (Marine drugs, 2018)
Keywords: Animals; Anti-inflammatory agents; Antigens, Differentiation - genetics; Antigens, Differentiation - metabolism; Body weight; Chemokine CXCL2 - genetics; Chemokine CXCL2 - metabolism; Colitis; Colitis - chemically induced; Colitis - drug therapy; Colon; colon inflammation; Complex Mixtures - chemistry; Complex Mixtures - pharmacology; Cucumaria - chemistry; Cucumaria frondosa; Cytokines; Cytokines - genetics; Cytokines - metabolism; Dextran; Dextran Sulfate; Dietary Supplements; Disease control; DNA; Drinking water; DSS colitis; ELISA; Enzyme-linked immunosorbent assay; Frondanol; Functional foods & nutraceuticals; Gene expression; Gene Expression Regulation - drug effects; Histology; Inflammation; Inflammatory bowel disease; Interleukin 6; Intestine; Intestines; Leukotriene B4; Lipids; Macrophage inflammatory protein; Macrophages; Male; Marine invertebrates; Mice; Mice, Inbred C57BL; Neutrophils; Nucleotide sequence; PCR; Peroxidase; Peroxidase - metabolism; Polymerase chain reaction; Proteins; RNA, Messenger - genetics; RNA, Messenger - metabolism; Rodents; Sodium; Sodium sulfate; Tissue; Tumor necrosis factor-α; DSS colitis; colon inflammation; Cucumaria frondosa; Frondanol