Griffithsin, a Highly Potent Broad-Spectrum Antiviral Lectin from Red Algae: From Discovery to Clinical Application

• Published in: Marine drugs Vol. 17; no. 10; p. 567
• Main Author: Lee, Choongho
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 06.10.2019; MDPI
• Subjects: Acquired immune deficiency syndrome; AIDS; Algae; Amino Acid Sequence; Amino acids; Animals; Antibodies; Antiviral activity; Antiviral agents; Antiviral Agents - pharmacology; Binding; Binding sites; Biocompatibility; carbohydrate-binding; Carbohydrates; Cytotoxicity; Disease transmission; Drug delivery; Epidemics; Glycoproteins; Glycosylation; griffithsin (grft); HIV; HIV Infections - drug therapy; HIV Infections - virology; HIV-1 - drug effects; Human immunodeficiency virus; human immunodeficiency virus (hiv); Humans; Immune system; Immunity; Immunosuppressive agents; In vivo methods and tests; Infections; lectin; Lectins; microbicide; Microbicides; Mutation; Neutralization; New class; NMR; Nuclear magnetic resonance; Pharmacokinetics; Plant Lectins - pharmacology; Plants; Proteins; Respiratory diseases; Review; Rhodophyta - chemistry; Toxicity; Vaccines; Viral diseases; Viroses; virus entry inhibitor; Viruses

griffithsin (GRFT); lectin; carbohydrate-binding; human immunodeficiency virus (HIV); microbicide; virus entry inhibitor.