Inula Japonica Thunb. Flower Ethanol Extract Improves Obesity and Exercise Endurance in Mice Fed A High-Fat Diet

• Published in: Nutrients Vol. 11; no. 1; p. 17
• Main Authors: Park, So-Hyun, Lee, Da-Hye, Kim, Min Jung, Ahn, Jiyun, Jang, Young-Jin, Ha, Tae-Youl, Jung, Chang Hwa
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 20.12.2018; MDPI
• Subjects: Adipocytes; Adipogenesis; Adipogenesis - drug effects; Animals; Anti-Obesity Agents - pharmacology; Apoptosis; Asteraceae; Atrophy; Diet, High-Fat - adverse effects; Endurance capacity; Ethanol; Ethanol - pharmacology; Exercise; exercise endurance; Fatigue tests; Flowers; Food; Grip strength; High fat diet; Immunoglobulins; Insulin; Inula japonica; Lipogenesis; Lipogenesis - drug effects; Male; Medical research; Mice; Mice, Inbred C57BL; mRNA; Muscles; Musculoskeletal system; myogenesis; Obesity; Obesity - drug therapy; Obesity - etiology; Obesity - physiopathology; Penicillin; Phosphatase; Physical Endurance - drug effects; Physical fitness; Phytotherapy - methods; Plant Extracts - pharmacology; Polymerase chain reaction; Proteins; Signal transduction; Skeletal muscle; Treadmills; Weight control; Weight Gain - drug effects; Asia; United States > US; China; Japan; Inula japonica; lipogenesis; adipogenesis; exercise endurance; myogenesis; obesity

Thunb. (Asteraceae) is a flowering plant that grows mainly in Korea, Japan, and China and its flower extract has diverse biological effects such as anti-inflammatory and antioxidative activities. However, the effects on obesity and enhancement of endurance capacity have not been explored yet. This s...