Decreased circulating transforming growth factor-beta (TGF-β) and kidney TGF-β immunoreactivity predict renal disease in cats with naturally occurring chronic kidney disease

• Published in: Journal of feline medicine and surgery Vol. 25; no. 12; p. 1098612X231208937
• Main Authors: Piyarungsri, Kakanang, Chuammitri, Phongsakorn, Pringproa, Kidsadagon, Pila, Pattiya, Srivorakul, Saralee, Sornpet, Benjaporn, Pusoonthornthum, Rosama
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.12.2023
• Subjects: Animals; atrophy; Atrophy - pathology; Atrophy - veterinary; blood serum; Cat Diseases - pathology; Cats; histopathology; immune response; immunohistochemistry; Kidney - metabolism; kidney diseases; kidneys; linear models; medicine; necropsy; Original; Renal Insufficiency, Chronic - metabolism; Renal Insufficiency, Chronic - veterinary; surgery; Transforming Growth Factor beta; Transforming Growth Factors; immunoreactivity; transforming growth factor-beta; Chronic kidney disease; tubular atrophy

Objectives The aim of the present study was to compare the circulating transforming growth factor-beta (TGF-β) of clinically normal age-matched and naturally occurring chronic kidney disease (CKD) cats and to determine the correlation between the TGF-β expression and histopathological changes in cat...