The Association between 25-Hydroxyvitamin D Concentration and Telomere Length in the Very-Old: The Newcastle 85+ Study

• Published in: Nutrients Vol. 13; no. 12; p. 4341
• Main Authors: Hakeem, Sarah, Mendonça, Nuno, Aspray, Terry, Kingston, Andrew, Martin-Ruiz, Carmen, Robinson, Louise, Hill, Tom R
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.12.2021; MDPI
• Subjects: 25-Hydroxyvitamin D; Adults; Age; Age Factors; Aged, 80 and over; ageing; Aging; Aging - blood; Aging - genetics; Aging - physiology; Alzheimer's disease; Biomarkers; Blood cells; Cell proliferation; Cross-Sectional Studies; DNA methylation; Female; Gene expression; Genetic testing; Humans; Lifestyles; Male; Medical records; Older people; Oxidative stress; Peripheral blood; Polymerase chain reaction; Population; Prospective Studies; Questionnaires; Telomerase; Telomere Homeostasis; telomere length; Telomeres; Vitamin D; Vitamin D - analogs & derivatives; Vitamin D - blood; Vitamin deficiency; Womens health; United Kingdom > UK; ageing; vitamin D; telomere length

(1) Introduction: vitamin D may maintain the telomere length, either directly or via the inflammation effect and/or modulating the rate of cell proliferation. Whilst results from cross-sectional studies investigating the association between 25(OH)D concentration and telomere length have been mixed,...