Natural Antioxidants and Hypertension: Promise and Challenges

• Published in: Cardiovascular therapeutics Vol. 28; no. 4; pp. e20 - e32
• Main Authors: Kizhakekuttu, Tinoy J., Widlansky, Michael E.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.08.2010
• Subjects: Antihypertensive Agents - adverse effects; Antihypertensive Agents - therapeutic use; Antioxidants; Antioxidants - adverse effects; Antioxidants - therapeutic use; Dietary Supplements - adverse effects; Humans; Hypertension; Hypertension - drug therapy; Hypertension - metabolism; Oxidative stress; Oxidative Stress - drug effects; Patient Selection; Reactive Oxygen Species - metabolism; Risk Assessment; Treatment Outcome

Hypertension reigns as a leading cause of cardiovascular morbidity and mortality worldwide. Excessive reactive oxygen species (ROS) have emerged as a central common pathway by which disparate influences may induce and exacerbate hypertension. Potential sources of excessive ROS in hypertension includ...