Lignin valorization meets synthetic biology
Lignin, an abundant renewable resource in nature, is a highly heterogeneous biopolymer consisting of phenylpropanoid units. It is essential for sustainable utilization of biomass to convert lignin to value‐added products. However, there are technical obstacles for lignin valorization due to intrinsi...
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| Published in | Engineering in life sciences Vol. 19; no. 6; pp. 463 - 470 |
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| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Germany
John Wiley and Sons Inc
01.06.2019
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1618-0240 1618-2863 |
| DOI | 10.1002/elsc.201800133 |
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| Abstract | Lignin, an abundant renewable resource in nature, is a highly heterogeneous biopolymer consisting of phenylpropanoid units. It is essential for sustainable utilization of biomass to convert lignin to value‐added products. However, there are technical obstacles for lignin valorization due to intrinsic heterogeneity. The emerging of synthetic biology technologies brings new opportunities for lignin breakdown and utilization. In this review, we discussed the applications of synthetic biology on lignin conversion, especially the production of value‐added products, such as aromatic chemicals, ring‐cleaved chemicals from lignin‐derived aromatics and bio‐active substances. Synthetic biology will offer new potential strategies for lignin valorization by optimizing lignin degradation enzymes, building novel artificial converting pathways, and improving the chassis of model microorganisms. |
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| AbstractList | Lignin, an abundant renewable resource in nature, is a highly heterogeneous biopolymer consisting of phenylpropanoid units. It is essential for sustainable utilization of biomass to convert lignin to value‐added products. However, there are technical obstacles for lignin valorization due to intrinsic heterogeneity. The emerging of synthetic biology technologies brings new opportunities for lignin breakdown and utilization. In this review, we discussed the applications of synthetic biology on lignin conversion, especially the production of value‐added products, such as aromatic chemicals, ring‐cleaved chemicals from lignin‐derived aromatics and bio‐active substances. Synthetic biology will offer new potential strategies for lignin valorization by optimizing lignin degradation enzymes, building novel artificial converting pathways, and improving the chassis of model microorganisms. Lignin, an abundant renewable resource in nature, is a highly heterogeneous biopolymer consisting of phenylpropanoid units. It is essential for sustainable utilization of biomass to convert lignin to value-added products. However, there are technical obstacles for lignin valorization due to intrinsic heterogeneity. The emerging of synthetic biology technologies brings new opportunities for lignin breakdown and utilization. In this review, we discussed the applications of synthetic biology on lignin conversion, especially the production of value-added products, such as aromatic chemicals, ring-cleaved chemicals from lignin-derived aromatics and bio-active substances. Synthetic biology will offer new potential strategies for lignin valorization by optimizing lignin degradation enzymes, building novel artificial converting pathways, and improving the chassis of model microorganisms.Lignin, an abundant renewable resource in nature, is a highly heterogeneous biopolymer consisting of phenylpropanoid units. It is essential for sustainable utilization of biomass to convert lignin to value-added products. However, there are technical obstacles for lignin valorization due to intrinsic heterogeneity. The emerging of synthetic biology technologies brings new opportunities for lignin breakdown and utilization. In this review, we discussed the applications of synthetic biology on lignin conversion, especially the production of value-added products, such as aromatic chemicals, ring-cleaved chemicals from lignin-derived aromatics and bio-active substances. Synthetic biology will offer new potential strategies for lignin valorization by optimizing lignin degradation enzymes, building novel artificial converting pathways, and improving the chassis of model microorganisms. |
| Author | Chang, Han‐Chen Zhang, Renkuan Li, Bing‐Zhi Chai, Meng‐Zhe Zhao, Chen‐Hui Yuan, Ying‐Jin |
| AuthorAffiliation | 2 Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) Tianjin University Tianjin P. R. China 1 Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education) School of Chemical Engineering and Technology Tianjin University Tianjin P. R. China |
| AuthorAffiliation_xml | – name: 1 Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education) School of Chemical Engineering and Technology Tianjin University Tianjin P. R. China – name: 2 Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) Tianjin University Tianjin P. R. China |
| Author_xml | – sequence: 1 givenname: Renkuan surname: Zhang fullname: Zhang, Renkuan organization: Tianjin University – sequence: 2 givenname: Chen‐Hui surname: Zhao fullname: Zhao, Chen‐Hui organization: Tianjin University – sequence: 3 givenname: Han‐Chen surname: Chang fullname: Chang, Han‐Chen organization: Tianjin University – sequence: 4 givenname: Meng‐Zhe surname: Chai fullname: Chai, Meng‐Zhe organization: Tianjin University – sequence: 5 givenname: Bing‐Zhi surname: Li fullname: Li, Bing‐Zhi email: bzli@tju.edu.cn organization: Tianjin University – sequence: 6 givenname: Ying‐Jin surname: Yuan fullname: Yuan, Ying‐Jin organization: Tianjin University |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32625023$$D View this record in MEDLINE/PubMed |
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| Keywords | synthetic biology value‐added products lignin valorization bio‐degradation artificial pathway |
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| SubjectTerms | artificial pathway bio‐degradation lignin valorization Review Reviews synthetic biology value‐added products |
| Title | Lignin valorization meets synthetic biology |
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