Identification and Biological Evaluation of Secondary Metabolites from the Endolichenic Fungus Aspergillus versicolor

A chemical investigation of the endolichenic fungus Aspergillus versicolor (125a), which was found in the lichen Lobaria quercizans, resulted in the isolation of four novel diphenyl ethers, named diorcinols F–H (1–3, resp.) and 3‐methoxyviolaceol‐II (4), eight new bisabolane sesquiterpenoids, named...

Full description

Saved in:
Bibliographic Details
Published inChemistry & biodiversity Vol. 12; no. 4; pp. 575 - 592
Main Authors Li, Xiao-Bin, Zhou, Yan-Hui, Zhu, Rong-Xiu, Chang, Wen-Qiang, Yuan, Hui-Qing, Gao, Wei, Zhang, Lu-Lu, Zhao, Zun-Tian, Lou, Hong-Xiang
Format Journal Article
LanguageEnglish
Published Zürich WILEY-VCH Verlag 01.04.2015
WILEY‐VCH Verlag
Wiley Subscription Services, Inc
Subjects
Acids
Antifungal activity
Antifungal Agents - chemistry
Antifungal Agents - isolation & purification
Antifungal Agents - pharmacology
Antineoplastic Agents, Phytogenic - chemistry
Antineoplastic Agents, Phytogenic - pharmacology
Aspergillus - chemistry
Aspergillus - metabolism
Aspergillus versicolor
Bioassays
Bisabolane sesquiterpenoid
Candida albicans
Candida albicans - drug effects
Cell Line, Tumor - drug effects
Circular Dichroism
Cytotoxic activity
Dichroism
Drug Evaluation, Preclinical - methods
Endolichenic fungus
Ethers
Fungi
Humans
Lichens - microbiology
Lobaria quercizans
Magnetic Resonance Spectroscopy
Metabolites
Molecular Structure
Phenyl Ethers - chemistry
Phenyl Ethers - pharmacology
Pyrogallol
Secondary Metabolism
Secondary metabolites
Sesquiterpenes - chemistry
Sesquiterpenes - isolation & purification
Sesquiterpenoids
Structure-Activity Relationship
Tumor cell lines
Endolichenic fungus
Fungi
Antifungal activity
Aspergillus versicolor
Sesquiterpenoids
Bisabolane sesquiterpenoid
Cytotoxic activity
Online AccessGet full text

Cover

Abstract A chemical investigation of the endolichenic fungus Aspergillus versicolor (125a), which was found in the lichen Lobaria quercizans, resulted in the isolation of four novel diphenyl ethers, named diorcinols F–H (1–3, resp.) and 3‐methoxyviolaceol‐II (4), eight new bisabolane sesquiterpenoids, named (−)‐(R)‐cyclo‐hydroxysydonic acid (5), (−)‐(7S,8R)‐8‐hydroxysydowic acid (6), (−)‐(7R,10S)‐10‐hydroxysydowic acid (7), (−)‐(7R,10R)‐iso‐10‐hydroxysydowic acid (8), (−)‐12‐acetoxy‐1‐deoxysydonic acid (9), (−)‐12‐acetoxysydonic acid (10), (−)‐12‐hydroxysydonic acid (11), and (−)‐(R)‐11‐dehydrosydonic acid (12), two new tris(pyrogallol ethers), named sydowiols D (13) and E (14), and fifteen known compounds, 15–29. All of the structures were determined by spectroscopic analyses, and a number of them were further identified through chemical transformations and electronic circular dichroism (ECD) calculations. Preliminary bioassays of these isolates for the determination of their inhibitory activities against the fungus Candida albicans, and their cytotoxicities against the human cancer cell lines PC3, A549, A2780, MDA‐MB‐231, and HEPG2 were also evaluated.
AbstractList A chemical investigation of the endolichenic fungus Aspergillus versicolor (125a), which was found in the lichen Lobaria quercizans, resulted in the isolation of four novel diphenyl ethers, named diorcinols F-H (1-3, resp.) and 3-methoxyviolaceol-II (4), eight new bisabolane sesquiterpenoids, named (-)-(R)-cyclo-hydroxysydonic acid (5), (-)-(7S,8R)-8-hydroxysydowic acid (6), (-)-(7R,10S)-10-hydroxysydowic acid (7), (-)-(7R,10R)-iso-10-hydroxysydowic acid (8), (-)-12-acetoxy-1-deoxysydonic acid (9), (-)-12-acetoxysydonic acid (10), (-)-12-hydroxysydonic acid (11), and (-)-(R)-11-dehydrosydonic acid (12), two new tris(pyrogallol ethers), named sydowiols D (13) and E (14), and fifteen known compounds, 15-29. All of the structures were determined by spectroscopic analyses, and a number of them were further identified through chemical transformations and electronic circular dichroism (ECD) calculations. Preliminary bioassays of these isolates for the determination of their inhibitory activities against the fungus Candida albicans, and their cytotoxicities against the human cancer cell lines PC3, A549, A2780, MDA-MB-231, and HEPG2 were also evaluated.
A chemical investigation of the endolichenic fungus Aspergillus versicolor (125a), which was found in the lichen Lobaria quercizans, resulted in the isolation of four novel diphenyl ethers, named diorcinols F-H (1-3, resp.) and 3-methoxyviolaceol-II (4), eight new bisabolane sesquiterpenoids, named (-)-(R)-cyclo-hydroxysydonic acid (5), (-)-(7S,8R)-8-hydroxysydowic acid (6), (-)-(7R,10S)-10-hydroxysydowic acid (7), (-)-(7R,10R)-iso-10-hydroxysydowic acid (8), (-)-12-acetoxy-1-deoxysydonic acid (9), (-)-12-acetoxysydonic acid (10), (-)-12-hydroxysydonic acid (11), and (-)-(R)-11-dehydrosydonic acid (12), two new tris(pyrogallol ethers), named sydowiols D (13) and E (14), and fifteen known compounds, 15-29. All of the structures were determined by spectroscopic analyses, and a number of them were further identified through chemical transformations and electronic circular dichroism (ECD) calculations. Preliminary bioassays of these isolates for the determination of their inhibitory activities against the fungus Candida albicans, and their cytotoxicities against the human cancer cell lines PC3, A549, A2780, MDA-MB-231, and HEPG2 were also evaluated.A chemical investigation of the endolichenic fungus Aspergillus versicolor (125a), which was found in the lichen Lobaria quercizans, resulted in the isolation of four novel diphenyl ethers, named diorcinols F-H (1-3, resp.) and 3-methoxyviolaceol-II (4), eight new bisabolane sesquiterpenoids, named (-)-(R)-cyclo-hydroxysydonic acid (5), (-)-(7S,8R)-8-hydroxysydowic acid (6), (-)-(7R,10S)-10-hydroxysydowic acid (7), (-)-(7R,10R)-iso-10-hydroxysydowic acid (8), (-)-12-acetoxy-1-deoxysydonic acid (9), (-)-12-acetoxysydonic acid (10), (-)-12-hydroxysydonic acid (11), and (-)-(R)-11-dehydrosydonic acid (12), two new tris(pyrogallol ethers), named sydowiols D (13) and E (14), and fifteen known compounds, 15-29. All of the structures were determined by spectroscopic analyses, and a number of them were further identified through chemical transformations and electronic circular dichroism (ECD) calculations. Preliminary bioassays of these isolates for the determination of their inhibitory activities against the fungus Candida albicans, and their cytotoxicities against the human cancer cell lines PC3, A549, A2780, MDA-MB-231, and HEPG2 were also evaluated.
A chemical investigation of the endolichenic fungus Aspergillus versicolor (125a), which was found in the lichen Lobaria quercizans , resulted in the isolation of four novel diphenyl ethers, named diorcinols F–H ( 1 – 3 , resp.) and 3‐methoxyviolaceol‐II ( 4 ), eight new bisabolane sesquiterpenoids, named (−)‐( R )‐cyclo‐hydroxysydonic acid ( 5 ), (−)‐(7 S ,8 R )‐8‐hydroxysydowic acid ( 6 ), (−)‐(7 R ,10 S )‐10‐hydroxysydowic acid ( 7 ), (−)‐(7 R ,10 R )‐iso‐10‐hydroxysydowic acid ( 8 ), (−)‐12‐acetoxy‐1‐deoxysydonic acid ( 9 ), (−)‐12‐acetoxysydonic acid ( 10 ), (−)‐12‐hydroxysydonic acid ( 11 ), and (−)‐( R )‐11‐dehydrosydonic acid ( 12 ), two new tris(pyrogallol ethers), named sydowiols D ( 13 ) and E ( 14 ), and fifteen known compounds, 15 – 29 . All of the structures were determined by spectroscopic analyses, and a number of them were further identified through chemical transformations and electronic circular dichroism (ECD) calculations. Preliminary bioassays of these isolates for the determination of their inhibitory activities against the fungus Candida albicans , and their cytotoxicities against the human cancer cell lines PC3, A549, A2780, MDA‐MB‐231, and HEPG2 were also evaluated.
A chemical investigation of the endolichenic fungus Aspergillus versicolor (125a), which was found in the lichen Lobaria quercizans, resulted in the isolation of four novel diphenyl ethers, named diorcinols F–H (1–3, resp.) and 3‐methoxyviolaceol‐II (4), eight new bisabolane sesquiterpenoids, named (−)‐(R)‐cyclo‐hydroxysydonic acid (5), (−)‐(7S,8R)‐8‐hydroxysydowic acid (6), (−)‐(7R,10S)‐10‐hydroxysydowic acid (7), (−)‐(7R,10R)‐iso‐10‐hydroxysydowic acid (8), (−)‐12‐acetoxy‐1‐deoxysydonic acid (9), (−)‐12‐acetoxysydonic acid (10), (−)‐12‐hydroxysydonic acid (11), and (−)‐(R)‐11‐dehydrosydonic acid (12), two new tris(pyrogallol ethers), named sydowiols D (13) and E (14), and fifteen known compounds, 15–29. All of the structures were determined by spectroscopic analyses, and a number of them were further identified through chemical transformations and electronic circular dichroism (ECD) calculations. Preliminary bioassays of these isolates for the determination of their inhibitory activities against the fungus Candida albicans, and their cytotoxicities against the human cancer cell lines PC3, A549, A2780, MDA‐MB‐231, and HEPG2 were also evaluated.
A chemical investigation of the endolichenic fungus Aspergillus versicolor (125a), which was found in the lichen Lobaria quercizans, resulted in the isolation of four novel diphenyl ethers, named diorcinols F-H (1-3, resp.) and 3-methoxyviolaceol-II (4), eight new bisabolane sesquiterpenoids, named (-)-(R)-cyclo-hydroxysydonic acid (5), (-)-(7S,8R)-8-hydroxysydow ic acid (6), (-)-(7R,10S)-10-hydroxysyd owic acid (7), (-)-(7R,10R)-iso-10-hydrox ysydowic acid (8), (-)-12-acetoxy-1-deoxysydonic acid (9), (-)-12-acetoxysydonic acid (10), (-)-12-hydroxysydonic acid (11), and (-)-(R)-11-dehydrosydonic acid (12), two new tris(pyrogallol ethers), named sydowiols D (13) and E (14), and fifteen known compounds, 15-29. All of the structures were determined by spectroscopic analyses, and a number of them were further identified through chemical transformations and electronic circular dichroism (ECD) calculations. Preliminary bioassays of these isolates for the determination of their inhibitory activities against the fungus Candida albicans, and their cytotoxicities against the human cancer cell lines PC3, A549, A2780, MDA-MB-231, and HEPG2 were also evaluated.
Author Zhu, Rong-Xiu
Yuan, Hui-Qing
Gao, Wei
Lou, Hong-Xiang
Zhang, Lu-Lu
Li, Xiao-Bin
Zhou, Yan-Hui
Chang, Wen-Qiang
Zhao, Zun-Tian
Author_xml – sequence: 1
  givenname: Xiao-Bin
  surname: Li
  fullname: Li, Xiao-Bin
  organization: Department of Natural Products Chemistry, Key Lab of Chemical Biology of Ministry of Education, School of Pharmaceutical Science, Shandong University, No. 44 West Wenhua Road, Jinan 250012, P. R. China (phone: +86-531-88382012; fax: +86-531-88382019)
– sequence: 2
  givenname: Yan-Hui
  surname: Zhou
  fullname: Zhou, Yan-Hui
  organization: Department of Natural Products Chemistry, Key Lab of Chemical Biology of Ministry of Education, School of Pharmaceutical Science, Shandong University, No. 44 West Wenhua Road, Jinan 250012, P. R. China (phone: +86-531-88382012; fax: +86-531-88382019)
– sequence: 3
  givenname: Rong-Xiu
  surname: Zhu
  fullname: Zhu, Rong-Xiu
  organization: School of Chemistry and Chemical Engineering, Shandong University, No. 27 Shanda Nanlu, Jinan 250100, P. R. China
– sequence: 4
  givenname: Wen-Qiang
  surname: Chang
  fullname: Chang, Wen-Qiang
  organization: Department of Natural Products Chemistry, Key Lab of Chemical Biology of Ministry of Education, School of Pharmaceutical Science, Shandong University, No. 44 West Wenhua Road, Jinan 250012, P. R. China (phone: +86-531-88382012; fax: +86-531-88382019)
– sequence: 5
  givenname: Hui-Qing
  surname: Yuan
  fullname: Yuan, Hui-Qing
  organization: Department of Biochemistry and Molecular Biology, School of Medicine, Shandong University, No. 44 West Wenhua Road, Jinan 250012, P. R. China
– sequence: 6
  givenname: Wei
  surname: Gao
  fullname: Gao, Wei
  organization: College of Life Sciences, Shandong Normal University, No. 88 East Wenhua Road, Jinan 250014, P. R. China
– sequence: 7
  givenname: Lu-Lu
  surname: Zhang
  fullname: Zhang, Lu-Lu
  organization: College of Life Sciences, Shandong Normal University, No. 88 East Wenhua Road, Jinan 250014, P. R. China
– sequence: 8
  givenname: Zun-Tian
  surname: Zhao
  fullname: Zhao, Zun-Tian
  organization: College of Life Sciences, Shandong Normal University, No. 88 East Wenhua Road, Jinan 250014, P. R. China
– sequence: 9
  givenname: Hong-Xiang
  surname: Lou
  fullname: Lou, Hong-Xiang
  email: louhongxiang@sdu.edu.cn
  organization: Department of Natural Products Chemistry, Key Lab of Chemical Biology of Ministry of Education, School of Pharmaceutical Science, Shandong University, No. 44 West Wenhua Road, Jinan 250012, P. R. China (phone: +86-531-88382012; fax: +86-531-88382019)
BackLink https://www.ncbi.nlm.nih.gov/pubmed/25879502$$D View this record in MEDLINE/PubMed
BookMark eNqNkktvEzEUhS1URNvAliUaiQ2bBNvjsWeWbUhDpbZIPAo7y2PfSV0cO9gzgf57XKaNUCUeC9tX19850n0coj0fPCD0nOAZwZi-1q3ZzigmDOfDH6EDwgmdkrrGe7tY0H10mNJ15nO-foL2aVWLpsL0AA2nBnxvO6tVb4MvlDfFsQ0urHLGFYutcsP4E7riA-jgjYo3xTn0qg3O9pCKLoZ10V9BsfAmp_QVeKuLk8GvhlQcpQ3ElXUux1uIyersHZ-ix51yCZ7dvRP06WTxcf52evZueTo_OptqJiifmqYF00KrhW6xqaqGmq7Upq5qYxqgbW1Iw7hRlGmFNeUKVMlLLHDJKBdClxP0avTdxPBtgNTLtU0anFMewpAk4TVmnArC_gMVjBIhWJ3Rlw_Q6zBEnwuRlDe56RXB1d-o7FWWvKH5nqAXd9TQrsHITbTr3GB5P6EMsBHQMaQUoZPa9r8m0kdlnSRY3i6CvF0EuVuELJs9kN07_1HQjILv1sHNP2g5P35z-bt2Ompt6uHHTqviV5krFZX8fLGU7-vlxRdWncvL8idcJtUa
CitedBy_id crossref_primary_10_4103_epj_epj_72_21
crossref_primary_10_1007_s11101_016_9473_1
crossref_primary_10_3390_molecules26133901
crossref_primary_10_1016_j_molstruc_2022_133302
crossref_primary_10_1021_acsomega_2c04434
crossref_primary_10_1016_j_funbio_2016_02_006
crossref_primary_10_1038_s41598_023_28773_z
crossref_primary_10_1007_s10600_016_1601_z
crossref_primary_10_3389_fphar_2022_986946
crossref_primary_10_1080_14786419_2023_2278158
crossref_primary_10_1007_s00284_024_03719_4
crossref_primary_10_1080_14786419_2023_2236764
crossref_primary_10_1128_spectrum_02582_21
crossref_primary_10_1039_C7CS00431A
crossref_primary_10_1016_j_phytol_2018_06_009
crossref_primary_10_3390_md21040234
crossref_primary_10_1080_14786419_2017_1363754
crossref_primary_10_1080_12298093_2022_2040112
crossref_primary_10_2174_1389557520666200925142514
crossref_primary_10_3390_md14030059
crossref_primary_10_2174_0122103155287990240117100232
crossref_primary_10_1039_C7NP00009J
crossref_primary_10_3390_molecules23061291
crossref_primary_10_1002_chem_202002442
crossref_primary_10_1016_j_phytochem_2021_113011
crossref_primary_10_3390_jof9030347
crossref_primary_10_5423_PPJ_NT_06_2024_0087
crossref_primary_10_1134_S0003683817010021
crossref_primary_10_3390_md16110451
crossref_primary_10_1016_j_phytochem_2021_112927
crossref_primary_10_3390_md17100563
crossref_primary_10_1007_s11101_018_9577_x
crossref_primary_10_1639_0007_2745_118_4_412
crossref_primary_10_1007_s11557_023_01934_0
crossref_primary_10_1016_j_phytol_2019_04_023
crossref_primary_10_1016_j_jksus_2021_101579
crossref_primary_10_11005_jbm_2019_26_2_113
crossref_primary_10_1021_np501018w
crossref_primary_10_1515_znc_2016_0138
crossref_primary_10_1155_2017_6961928
crossref_primary_10_1080_12298093_2021_1976967
crossref_primary_10_1016_j_phytol_2023_05_004
crossref_primary_10_1016_j_bioorg_2024_107107
crossref_primary_10_1080_22311866_2021_2021986
crossref_primary_10_1016_j_phytochem_2022_113245
crossref_primary_10_1039_C5NP00134J
crossref_primary_10_1021_acs_jnatprod_5b00998
crossref_primary_10_1111_1462_2920_13858
crossref_primary_10_1002_cbdv_202200178
crossref_primary_10_3390_jcm7100345
crossref_primary_10_1016_j_sajb_2019_12_008
crossref_primary_10_3390_biom10101385
crossref_primary_10_1016_j_phymed_2018_01_006
crossref_primary_10_1038_s41429_018_0058_7
crossref_primary_10_1021_acs_jnatprod_2c01022
crossref_primary_10_1016_j_tibtech_2017_03_003
crossref_primary_10_1016_j_bmcl_2017_01_032
crossref_primary_10_1177_1934578X1601100633
crossref_primary_10_3390_md17050262
crossref_primary_10_1016_j_phytochem_2020_112521
crossref_primary_10_2174_1570193X20666230707140919
crossref_primary_10_1016_j_bioorg_2020_104420
crossref_primary_10_3390_molecules28010062
crossref_primary_10_1080_10286020_2024_2443086
crossref_primary_10_1177_1934578X231213220
crossref_primary_10_1016_j_fitote_2024_106136
crossref_primary_10_3389_fbioe_2022_1011220
crossref_primary_10_1021_acs_jnatprod_6b00197
crossref_primary_10_1016_j_simyco_2020_05_002
crossref_primary_10_1134_S1068162020060023
Cites_doi 10.1016/j.phytochem.2004.08.020
10.1016/0022-1759(83)90303-4
10.1007/s11172-010-0173-5
10.1021/np960542n
10.1248/cpb.30.514
10.1016/j.bmc.2013.04.004
10.1016/j.phytochem.2004.12.031
10.1039/c39920000646
10.1021/jo0611059
10.1021/np100909y
10.3390/md10010234
10.1021/np400465r
10.1016/S0957-4166(99)00359-6
10.1016/S0031-9422(00)88601-X
10.1021/np800777f
10.1128/AAC.00940-08
10.1016/S0031-9422(01)00394-6
10.1021/np2009362
10.1021/jp0275802
10.1002/chir.20733
10.1271/bbb1961.42.37
10.1071/CH9842349
10.2307/3759302
10.1002/cbdv.201000067
10.1002/anie.201104488
10.1002/mrc.1974
10.1246/cl.1978.797
10.1021/ol016737q
10.1063/1.472829
10.1248/cpb.41.2040
10.1038/ja.2013.40
10.1021/jp980939v
10.1016/j.steroids.2013.05.007
10.1248/cpb.55.304
10.1021/np50123a008
10.1021/np0102758
10.1039/p19900002715
10.1016/S0031-9422(00)84399-X
10.1002/mrc.1260250502
10.1271/bbb1961.39.2337
10.1016/j.fitote.2013.08.002
10.1021/np100059m
10.1016/j.fitote.2012.05.002
10.1021/j100007a062
10.1021/np200614h
10.1021/np200769q
10.1016/j.tetlet.2013.08.137
10.1016/j.scitotenv.2011.06.010
10.1002/jlac.197819780811
10.1021/ol102168z
10.1248/cpb.51.794
ContentType Journal Article
Copyright Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich
Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich.
Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zurich
Copyright Wiley Subscription Services, Inc. Apr 2015
Copyright_xml – notice: Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich
– notice: Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich.
– notice: Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zurich
– notice: Copyright Wiley Subscription Services, Inc. Apr 2015
DBID BSCLL
AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7QO
7TM
8FD
FR3
K9.
M7N
P64
7X8
7ST
7U6
C1K
DOI 10.1002/cbdv.201400146
DatabaseName Istex
CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
Biotechnology Research Abstracts
Nucleic Acids Abstracts
Technology Research Database
Engineering Research Database
ProQuest Health & Medical Complete (Alumni)
Algology Mycology and Protozoology Abstracts (Microbiology C)
Biotechnology and BioEngineering Abstracts
MEDLINE - Academic
Environment Abstracts
Sustainability Science Abstracts
Environmental Sciences and Pollution Management
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
Biotechnology Research Abstracts
Technology Research Database
Algology Mycology and Protozoology Abstracts (Microbiology C)
Nucleic Acids Abstracts
ProQuest Health & Medical Complete (Alumni)
Engineering Research Database
Biotechnology and BioEngineering Abstracts
MEDLINE - Academic
Environment Abstracts
Sustainability Science Abstracts
Environmental Sciences and Pollution Management
DatabaseTitleList MEDLINE
MEDLINE - Academic
CrossRef

Environment Abstracts
Biotechnology Research Abstracts
Biotechnology Research Abstracts
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Biology
EISSN 1612-1880
EndPage 592
ExternalDocumentID 3656028651
25879502
10_1002_cbdv_201400146
CBDV201400146
ark_67375_WNG_R8GNX45M_V
Genre article
Research Support, Non-U.S. Gov't
Journal Article
GroupedDBID ---
.3N
.GA
.Y3
05W
0R~
10A
1L6
1OC
29B
31~
33P
3SF
3WU
4.4
50Y
50Z
51W
51X
52M
52N
52O
52P
52S
52T
52U
52W
52X
53G
5GY
5VS
66C
702
7PT
8-0
8-1
8-3
8-4
8-5
8UM
930
A03
AAESR
AAEVG
AAHHS
AANLZ
AAONW
AASGY
AAXRX
AAZKR
ABCQN
ABCUV
ABEML
ABIJN
ABJNI
ABPVW
ACAHQ
ACBWZ
ACCFJ
ACCZN
ACGFS
ACIWK
ACPOU
ACPRK
ACSCC
ACXBN
ACXQS
ADBBV
ADEOM
ADIZJ
ADKYN
ADMGS
ADOZA
ADXAS
ADZMN
ADZOD
AEEZP
AEIGN
AEIMD
AENEX
AEQDE
AEUQT
AEUYR
AFBPY
AFFPM
AFGKR
AFPWT
AFRAH
AFZJQ
AHBTC
AHMBA
AITYG
AIURR
AIWBW
AJBDE
AJXKR
ALAGY
ALMA_UNASSIGNED_HOLDINGS
ALUQN
AMBMR
AMYDB
ASPBG
ATUGU
AUFTA
AVWKF
AZBYB
AZFZN
AZVAB
BAFTC
BDRZF
BFHJK
BHBCM
BMNLL
BMXJE
BNHUX
BROTX
BRXPI
BSCLL
BY8
CS3
D-E
D-F
DCZOG
DPXWK
DR2
DRFUL
DRSTM
DU5
EBD
EBS
EJD
EMOBN
F00
F01
F04
F5P
FEDTE
G-S
G.N
GNP
GODZA
H.T
H.X
HBH
HF~
HGLYW
HHY
HHZ
HVGLF
HZ~
IX1
J0M
JPC
KQQ
LATKE
LAW
LC2
LC3
LEEKS
LH4
LITHE
LOXES
LP6
LP7
LUTES
LW6
LYRES
MEWTI
MK4
MRFUL
MRSTM
MSFUL
MSSTM
MXFUL
MXSTM
N04
N05
N9A
NF~
O66
O9-
OIG
P2P
P2W
P2X
P4D
PQQKQ
Q.N
Q11
QB0
QRW
R.K
ROL
RWI
RX1
RYL
SUPJJ
SV3
UB1
V2E
W8V
W99
WBFHL
WBKPD
WIH
WIK
WJL
WOHZO
WQJ
WRC
WXSBR
WYISQ
XG1
XV2
ZZTAW
~IA
~WT
AAHQN
AAMNL
AANHP
AAYCA
ACRPL
ACYXJ
ADNMO
AFWVQ
ALVPJ
AAYXX
AEYWJ
AGHNM
AGQPQ
AGYGG
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7QO
7TM
8FD
AAMMB
AEFGJ
AGXDD
AIDQK
AIDYY
FR3
K9.
M7N
P64
7X8
7ST
7U6
C1K
ID FETCH-LOGICAL-c4726-d9bedbebc7cb0d5592df3cd858dd9e2b8d1946da24ca0c26aea363070342677c3
IEDL.DBID DR2
ISSN 1612-1872
1612-1880
IngestDate Fri Jul 11 03:50:49 EDT 2025
Thu Jul 10 19:28:02 EDT 2025
Fri Jul 25 12:09:04 EDT 2025
Sun Jul 13 05:34:08 EDT 2025
Wed Feb 19 02:09:47 EST 2025
Tue Jul 01 00:43:37 EDT 2025
Thu Apr 24 22:56:48 EDT 2025
Wed Jan 22 17:03:07 EST 2025
Wed Oct 30 09:48:44 EDT 2024
IsPeerReviewed true
IsScholarly true
Issue 4
Keywords Endolichenic fungus
Fungi
Antifungal activity
Aspergillus versicolor
Sesquiterpenoids
Bisabolane sesquiterpenoid
Cytotoxic activity
Language English
License http://onlinelibrary.wiley.com/termsAndConditions#vor
Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c4726-d9bedbebc7cb0d5592df3cd858dd9e2b8d1946da24ca0c26aea363070342677c3
Notes istex:B5F1DC94E6AB1586485C7D14E292F37508765629
ArticleID:CBDV201400146
ark:/67375/WNG-R8GNX45M-V
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
PMID 25879502
PQID 1673369273
PQPubID 986337
PageCount 18
ParticipantIDs proquest_miscellaneous_1680462714
proquest_miscellaneous_1674217748
proquest_journals_2691615105
proquest_journals_1673369273
pubmed_primary_25879502
crossref_citationtrail_10_1002_cbdv_201400146
crossref_primary_10_1002_cbdv_201400146
wiley_primary_10_1002_cbdv_201400146_CBDV201400146
istex_primary_ark_67375_WNG_R8GNX45M_V
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2015-04
April 2015
2015-04-00
2015-Apr
20150401
PublicationDateYYYYMMDD 2015-04-01
PublicationDate_xml – month: 04
  year: 2015
  text: 2015-04
PublicationDecade 2010
PublicationPlace Zürich
PublicationPlace_xml – name: Zürich
– name: Switzerland
– name: Weinheim
PublicationTitle Chemistry & biodiversity
PublicationTitleAlternate Chemistry & Biodiversity
PublicationYear 2015
Publisher WILEY-VCH Verlag
WILEY‐VCH Verlag
Wiley Subscription Services, Inc
Publisher_xml – name: WILEY-VCH Verlag
– name: WILEY‐VCH Verlag
– name: Wiley Subscription Services, Inc
References Y.-F. Huang , X.-X. Li , G.-D. Chen , H. Gao , L.-D. Guo , X.-S. Yao , Junwu Xuebao 2012, 31, 769.
J. Hargreaves , J. Park , E. L. Ghisalberti , K. Sivasithamparam , B. W. Skelton , A. H. White , J. Nat. Prod. 2002, 65, 7.
D. Li , Y. Xu , C.-L. Shao , R.-Y. Yang , C.-J. Zheng , Y.-Y. Chen , X.-M. Fu , P.-Y. Qian , Z.-G. She , N. J. de Voogd , Mar. Drugs 2012, 10, 234.
X. Fu , F. J. Schmitz , M. Govindan , S. A. Abbas , K. M. Hanson , P. A. Horton , P. Crews , M. Laney , R. C. Schatzman , J. Nat. Prod. 1995, 58, 1384.
Y.-C. Wang , S.-B. Niu , S.-C. Liu , L.-D. Guo , Y.-S. Che , Org. Lett. 2010, 12, 5081.
H. Sun , J. Phys. Chem. B 1998, 102, 7338.
H. Kropf , H. Von Wallis , J. Chem. Res., Synop. 1983, 11, 282.
G. T. Yogui , J. L. Sericano , R. C. Montone , Sci. Total Environ. 2011, 409, 3902.
F. Zhang , L. Li , S.-B. Niu , Y.-K. Si , L.-D. Guo , X.-J. Jiang , Y.-S. Che , J. Nat. Prod. 2012, 75, 230.
T. Bunyapaiboonsri , S. Yoiprommarat , K. Intereya , K. Kocharin , Chem. Pharm. Bull. 2007, 55, 304.
K. Shibata , T. Kamikawa , N. Kaneda , M. Taniguchi , Chem. Lett. 1978, 7, 797.
W. Wu , H.-Q. Dai , L. Bao , B. Ren , J.-C. Lu , Y.-M. Luo , L.-D. Guo , L.-X. Zhang , H.-W. Liu , J. Nat. Prod. 2011, 74, 1303.
A. Klamt , J. Phys. Chem. 1995, 99, 2224.
T. Mosmann , J. Immunol. Methods 1983, 65, 55.
T. Tanahashi , Y. Takenaka , N. Nagakura , N. Hamada , Phytochemistry 2001, 58, 1129.
H.-Q. Gao , L.-N. Zhou , S.-X. Cai , G.-J. Zhang , T.-J. Zhu , Q.-Q. Gu , D.-H. Li , J. Antibiot. 2013, 66, 539.
A. N. Yurchenko , O. F. Smetanina , A. I. Kalinovsky , M. V. Pivkin , P. S. Dmitrenok , T. A. Kuznetsova , Russ. Chem. Bull., Int. Ed. 2010, 59, 852.
J. A. Ballantine , C. H. Hassall , B. D. Jones , Phytochemistry 1968, 7, 1529.
C.-L. Shao , Z.-G. She , Z.-Y. Guo , H. Peng , X.-L. Cai , S.-N. Zhou , Y.-C. Gu , Y.-C. Lin , Magn. Reson. Chem. 2007, 45, 434.
G. Li , H.-Y. Wang , R.-X. Zhu , L.-M. Sun , L.-N. Wang , M. Li , Y.-Y. Li , Y.-Q. Liu , Z.-T. Zhao , H.-X. Lou , J. Nat. Prod. 2012, 75, 142.
T. Itabashi , K. Nozawa , S. Nakajima , K. Kawai , Chem. Pharm. Bull. 1993, 41, 2040.
M. Chen , C.-L. Shao , X.-M. Fu , R.-F. Xu , J.-J. Zheng , D.-L. Zhao , Z.-G. She , C.-Y. Wang , J. Nat. Prod. 2013, 76, 1229.
J. A. Elix , A. J. Jones , L. Lajide , B. J. Coppins , P. W. James , Aust. J. Chem. 1984, 37, 2349.
Q.-C. Zheng , G.-D. Chen , M.-Z. Kong , G.-Q. Li , J.-Y. Cui , X.-X. Li , Z.-Y. Wu , L.-D. Guo , Y.-Z. Cen , Y.-Z. Zheng , H. Gao , Steroids 2013, 78, 896.
T. Hamasaki , Y. Sato , Y. Hatsuda , Agric. Biol. Chem. 1975, 39, 2337.
X. Fu , F. J. Schmitz , J. Nat. Prod. 1996, 59, 1102.
X.-R. Liu , F.-H. Song , L. Ma , C.-X. Chen , X. Xiao , B. Ren , X.-T. Liu , H.-Q. Dai , A. M. Piggott , Y. Av-Gay , L.-X. Zhang , R. J. Capon , Tetrahedron Lett. 2013, 54, 6081.
L. J. Fremlin , A. M. Piggott , E. Lacey , R. J. Capon , J. Nat. Prod. 2009, 72, 666.
A. Klamt , V. Jonas , J. Chem. Phys. 1996, 105, 9972.
Q.-X. Wang , L. Bao , X.-L. Yang , D.-L. Liu , H. Guo , H.-Q. Dai , F.-H. Song , L.-X. Zhang , L.-D. Guo , S.-J. Li , H.-W. Liu , Fitoterapia 2013, 90, 220.
Y. M. Chung , C. K. Wei , D. W. Chuang , M. El-Shazly , C. T. Hsieh , T. Asai , Y. Oshima , T. J. Hsieh , T. L. Hwang , Y. C. Wu , F. R. Chang , Bioorg. Med. Chem. 2013, 21, 3866.
Z.-Y. Lu , H.-J. Zhu , P. Fu , Y. Wang , Z.-H. Zhang , H.-P. Lin , P.-P. Liu , Y.-B. Zhuang , K. Hong , W.-M. Zhu , J. Nat. Prod. 2010, 73, 911.
R. A. Werner , A. Rossmann , C. Schwarz , A. Bacher , H.-L. Schmidt , W. Eisenreich , Phytochemistry 2004, 65, 2809.
P. J. Stephens , N. Harada , Chirality 2010, 22, 229.
C. Diedrich , S. Grimme , J. Phys. Chem. A 2003, 107, 2524.
D. G. I. Kingston , P. N. Chen , J. R. Vercellotti , Phytochemistry 1976, 15, 1037.
J.-W. He , G.-D. Chen , H. Gao , F. Yang , X.-X. Li , T. Peng , L.-D. Guo , X.-S. Yao , Fitoterapia 2012, 83, 1087.
E. M. K. Wijeratne , B. P. Bashyal , M. X. Liu , D. D. Rocha , G. M. K. B. Gunaherath , J. M. U'Ren , M. K. Gunatilaka , A. E. Arnold , L. Whitesell , A. A. L. Gunatilaka , J. Nat. Prod. 2012, 75, 361.
L.-M. Sun , S.-J. Sun , A.-X. Cheng , X.-Z. Wu , Y. Zhang , H.-X. Lou , Antimicrob. Agents Chemother. 2009, 53, 1586.
T. Hamasaki , K. Nagayama , Y. Hatsuda , Agric. Biol. Chem. 1978, 42, 37.
G. Vidari , A. Di Rosa , G. Zanoni , C. Bicchi , Tetrahedron: Asymmetry 1999, 10, 3547.
M. S. R. Nair , S. T. Carey , Mycologia 1979, 71, 1089.
Y. Takenaka , N. Hamada , T. Tanahashi , Phytochemistry 2005, 66, 665.
J. Magano , M. H. Chen , J. D. Clark , T. Nussbaumer , J. Org. Chem. 2006, 71, 7103.
M. S. Morales-Ríos , J. Espiñeira , P. Joseph-Nathan , Magn. Reson. Chem. 1987, 25, 377.
J. B. Spencer , P. M. Jordan , J. Chem. Soc., Chem. Commun. 1992, 8, 646.
Y. Takenaka , T. Tanahashi , N. Nagakura , N. Hamada , Chem. Pharm. Bull. 2003, 51, 794.
G. H. Yang , K. Yun , V. N. Nenkep , H. D. Choi , J. S. Kang , B. W. Son , Chem. Biodiversity 2010, 7, 2766.
W. A. König , K. P. Pfaff , W. Loeffler , D. Schanz , H. Zähner , Liebigs Ann. Chem. 1978, 8, 1289.
K. Scherlach , H. W. Nützmann , V. Schroeckh , H. M. Dahse , A. A. Brakhage , C. Hertweck , Angew. Chem., Int. Ed. 2011, 50, 9843.
M. M. Wagenaar , D. M. Gibson , J. Clardy , Org. Lett. 2002, 4, 671.
A. R. Howell , G. Pattenden , J. Chem. Soc., Perkin Trans. 1 1990, 10, 2715.
M. Yamazaki , Y. Maebayashi , Chem. Pharm. Bull. 1982, 30, 514.
2010; 12
1968; 7
2004; 65
2006; 71
1990; 10
2010; 59
2013; 66
2013; 21
1983; 6
2003; 51
2012; 10
2005; 66
1978; 8
1979; 71
1983; 11
1978; 7
1996; 105
2010; 22
1992; 8
2009; 53
2013; 54
2011; 409
1999; 10
2001; 58
2010; 7
2010; 73
2012; 83
1995; 58
1975; 39
1982; 30
1995; 99
1993; 41
2011; 74
2013; 90
2002; 4
2007; 55
1996; 59
2012; 75
2012; 31
1987; 25
2003; 107
1984; 37
2013; 76
2009; 72
2013; 78
1978; 42
2002; 65
2011; 50
1998; 102
2007; 45
1976; 15
e_1_2_1_41_2
e_1_2_1_22_2
e_1_2_1_45_2
e_1_2_1_20_2
e_1_2_1_43_2
e_1_2_1_26_2
e_1_2_1_49_2
e_1_2_1_24_2
e_1_2_1_47_2
Kropf H. (e_1_2_1_16_2) 1983; 11
e_1_2_1_28_2
e_1_2_1_6_2
e_1_2_1_54_2
e_1_2_1_4_2
e_1_2_1_2_2
e_1_2_1_12_2
e_1_2_1_33_2
e_1_2_1_50_2
e_1_2_1_10_2
e_1_2_1_31_2
e_1_2_1_52_2
e_1_2_1_37_2
e_1_2_1_14_2
e_1_2_1_35_2
e_1_2_1_8_2
e_1_2_1_18_2
e_1_2_1_39_2
Huang Y.‐F. (e_1_2_1_40_2) 2012; 31
e_1_2_1_23_2
e_1_2_1_44_2
e_1_2_1_21_2
e_1_2_1_42_2
e_1_2_1_27_2
e_1_2_1_48_2
e_1_2_1_25_2
e_1_2_1_46_2
e_1_2_1_29_2
e_1_2_1_30_2
e_1_2_1_53_2
e_1_2_1_7_2
e_1_2_1_5_2
e_1_2_1_11_2
e_1_2_1_34_2
e_1_2_1_3_2
e_1_2_1_32_2
e_1_2_1_51_2
e_1_2_1_1_2
e_1_2_1_15_2
e_1_2_1_38_2
e_1_2_1_13_2
e_1_2_1_36_2
e_1_2_1_19_2
e_1_2_1_17_2
e_1_2_1_9_2
References_xml – reference: X. Fu , F. J. Schmitz , J. Nat. Prod. 1996, 59, 1102.
– reference: J. B. Spencer , P. M. Jordan , J. Chem. Soc., Chem. Commun. 1992, 8, 646.
– reference: C. Diedrich , S. Grimme , J. Phys. Chem. A 2003, 107, 2524.
– reference: J. A. Ballantine , C. H. Hassall , B. D. Jones , Phytochemistry 1968, 7, 1529.
– reference: H.-Q. Gao , L.-N. Zhou , S.-X. Cai , G.-J. Zhang , T.-J. Zhu , Q.-Q. Gu , D.-H. Li , J. Antibiot. 2013, 66, 539.
– reference: A. N. Yurchenko , O. F. Smetanina , A. I. Kalinovsky , M. V. Pivkin , P. S. Dmitrenok , T. A. Kuznetsova , Russ. Chem. Bull., Int. Ed. 2010, 59, 852.
– reference: E. M. K. Wijeratne , B. P. Bashyal , M. X. Liu , D. D. Rocha , G. M. K. B. Gunaherath , J. M. U'Ren , M. K. Gunatilaka , A. E. Arnold , L. Whitesell , A. A. L. Gunatilaka , J. Nat. Prod. 2012, 75, 361.
– reference: H. Sun , J. Phys. Chem. B 1998, 102, 7338.
– reference: T. Hamasaki , Y. Sato , Y. Hatsuda , Agric. Biol. Chem. 1975, 39, 2337.
– reference: L. J. Fremlin , A. M. Piggott , E. Lacey , R. J. Capon , J. Nat. Prod. 2009, 72, 666.
– reference: W. A. König , K. P. Pfaff , W. Loeffler , D. Schanz , H. Zähner , Liebigs Ann. Chem. 1978, 8, 1289.
– reference: M. Chen , C.-L. Shao , X.-M. Fu , R.-F. Xu , J.-J. Zheng , D.-L. Zhao , Z.-G. She , C.-Y. Wang , J. Nat. Prod. 2013, 76, 1229.
– reference: J.-W. He , G.-D. Chen , H. Gao , F. Yang , X.-X. Li , T. Peng , L.-D. Guo , X.-S. Yao , Fitoterapia 2012, 83, 1087.
– reference: Y. M. Chung , C. K. Wei , D. W. Chuang , M. El-Shazly , C. T. Hsieh , T. Asai , Y. Oshima , T. J. Hsieh , T. L. Hwang , Y. C. Wu , F. R. Chang , Bioorg. Med. Chem. 2013, 21, 3866.
– reference: K. Shibata , T. Kamikawa , N. Kaneda , M. Taniguchi , Chem. Lett. 1978, 7, 797.
– reference: J. Hargreaves , J. Park , E. L. Ghisalberti , K. Sivasithamparam , B. W. Skelton , A. H. White , J. Nat. Prod. 2002, 65, 7.
– reference: J. Magano , M. H. Chen , J. D. Clark , T. Nussbaumer , J. Org. Chem. 2006, 71, 7103.
– reference: L.-M. Sun , S.-J. Sun , A.-X. Cheng , X.-Z. Wu , Y. Zhang , H.-X. Lou , Antimicrob. Agents Chemother. 2009, 53, 1586.
– reference: M. M. Wagenaar , D. M. Gibson , J. Clardy , Org. Lett. 2002, 4, 671.
– reference: D. Li , Y. Xu , C.-L. Shao , R.-Y. Yang , C.-J. Zheng , Y.-Y. Chen , X.-M. Fu , P.-Y. Qian , Z.-G. She , N. J. de Voogd , Mar. Drugs 2012, 10, 234.
– reference: A. R. Howell , G. Pattenden , J. Chem. Soc., Perkin Trans. 1 1990, 10, 2715.
– reference: G. H. Yang , K. Yun , V. N. Nenkep , H. D. Choi , J. S. Kang , B. W. Son , Chem. Biodiversity 2010, 7, 2766.
– reference: M. Yamazaki , Y. Maebayashi , Chem. Pharm. Bull. 1982, 30, 514.
– reference: M. S. Morales-Ríos , J. Espiñeira , P. Joseph-Nathan , Magn. Reson. Chem. 1987, 25, 377.
– reference: T. Itabashi , K. Nozawa , S. Nakajima , K. Kawai , Chem. Pharm. Bull. 1993, 41, 2040.
– reference: M. S. R. Nair , S. T. Carey , Mycologia 1979, 71, 1089.
– reference: J. A. Elix , A. J. Jones , L. Lajide , B. J. Coppins , P. W. James , Aust. J. Chem. 1984, 37, 2349.
– reference: T. Hamasaki , K. Nagayama , Y. Hatsuda , Agric. Biol. Chem. 1978, 42, 37.
– reference: W. Wu , H.-Q. Dai , L. Bao , B. Ren , J.-C. Lu , Y.-M. Luo , L.-D. Guo , L.-X. Zhang , H.-W. Liu , J. Nat. Prod. 2011, 74, 1303.
– reference: Q.-C. Zheng , G.-D. Chen , M.-Z. Kong , G.-Q. Li , J.-Y. Cui , X.-X. Li , Z.-Y. Wu , L.-D. Guo , Y.-Z. Cen , Y.-Z. Zheng , H. Gao , Steroids 2013, 78, 896.
– reference: Y.-C. Wang , S.-B. Niu , S.-C. Liu , L.-D. Guo , Y.-S. Che , Org. Lett. 2010, 12, 5081.
– reference: P. J. Stephens , N. Harada , Chirality 2010, 22, 229.
– reference: C.-L. Shao , Z.-G. She , Z.-Y. Guo , H. Peng , X.-L. Cai , S.-N. Zhou , Y.-C. Gu , Y.-C. Lin , Magn. Reson. Chem. 2007, 45, 434.
– reference: X.-R. Liu , F.-H. Song , L. Ma , C.-X. Chen , X. Xiao , B. Ren , X.-T. Liu , H.-Q. Dai , A. M. Piggott , Y. Av-Gay , L.-X. Zhang , R. J. Capon , Tetrahedron Lett. 2013, 54, 6081.
– reference: A. Klamt , J. Phys. Chem. 1995, 99, 2224.
– reference: G. Vidari , A. Di Rosa , G. Zanoni , C. Bicchi , Tetrahedron: Asymmetry 1999, 10, 3547.
– reference: R. A. Werner , A. Rossmann , C. Schwarz , A. Bacher , H.-L. Schmidt , W. Eisenreich , Phytochemistry 2004, 65, 2809.
– reference: T. Mosmann , J. Immunol. Methods 1983, 65, 55.
– reference: H. Kropf , H. Von Wallis , J. Chem. Res., Synop. 1983, 11, 282.
– reference: D. G. I. Kingston , P. N. Chen , J. R. Vercellotti , Phytochemistry 1976, 15, 1037.
– reference: G. T. Yogui , J. L. Sericano , R. C. Montone , Sci. Total Environ. 2011, 409, 3902.
– reference: T. Bunyapaiboonsri , S. Yoiprommarat , K. Intereya , K. Kocharin , Chem. Pharm. Bull. 2007, 55, 304.
– reference: F. Zhang , L. Li , S.-B. Niu , Y.-K. Si , L.-D. Guo , X.-J. Jiang , Y.-S. Che , J. Nat. Prod. 2012, 75, 230.
– reference: G. Li , H.-Y. Wang , R.-X. Zhu , L.-M. Sun , L.-N. Wang , M. Li , Y.-Y. Li , Y.-Q. Liu , Z.-T. Zhao , H.-X. Lou , J. Nat. Prod. 2012, 75, 142.
– reference: T. Tanahashi , Y. Takenaka , N. Nagakura , N. Hamada , Phytochemistry 2001, 58, 1129.
– reference: Y.-F. Huang , X.-X. Li , G.-D. Chen , H. Gao , L.-D. Guo , X.-S. Yao , Junwu Xuebao 2012, 31, 769.
– reference: Y. Takenaka , T. Tanahashi , N. Nagakura , N. Hamada , Chem. Pharm. Bull. 2003, 51, 794.
– reference: Y. Takenaka , N. Hamada , T. Tanahashi , Phytochemistry 2005, 66, 665.
– reference: A. Klamt , V. Jonas , J. Chem. Phys. 1996, 105, 9972.
– reference: K. Scherlach , H. W. Nützmann , V. Schroeckh , H. M. Dahse , A. A. Brakhage , C. Hertweck , Angew. Chem., Int. Ed. 2011, 50, 9843.
– reference: X. Fu , F. J. Schmitz , M. Govindan , S. A. Abbas , K. M. Hanson , P. A. Horton , P. Crews , M. Laney , R. C. Schatzman , J. Nat. Prod. 1995, 58, 1384.
– reference: Z.-Y. Lu , H.-J. Zhu , P. Fu , Y. Wang , Z.-H. Zhang , H.-P. Lin , P.-P. Liu , Y.-B. Zhuang , K. Hong , W.-M. Zhu , J. Nat. Prod. 2010, 73, 911.
– reference: Q.-X. Wang , L. Bao , X.-L. Yang , D.-L. Liu , H. Guo , H.-Q. Dai , F.-H. Song , L.-X. Zhang , L.-D. Guo , S.-J. Li , H.-W. Liu , Fitoterapia 2013, 90, 220.
– volume: 75
  start-page: 361
  year: 2012
  publication-title: J. Nat. Prod.
– volume: 4
  start-page: 671
  year: 2002
  publication-title: Org. Lett.
– volume: 58
  start-page: 1129
  year: 2001
  publication-title: Phytochemistry
– volume: 99
  start-page: 2224
  year: 1995
  publication-title: J. Phys. Chem.
– volume: 45
  start-page: 434
  year: 2007
  publication-title: Magn. Reson. Chem.
– volume: 10
  start-page: 234
  year: 2012
  publication-title: Mar. Drugs
– volume: 8
  start-page: 1289
  year: 1978
  publication-title: Liebigs Ann. Chem.
– volume: 10
  start-page: 2715
  year: 1990
  publication-title: J. Chem. Soc., Perkin Trans. 1
– volume: 73
  start-page: 911
  year: 2010
  publication-title: J. Nat. Prod.
– volume: 22
  start-page: 229
  year: 2010
  publication-title: Chirality
– volume: 6
  start-page: 55
  year: 1983
  publication-title: J. Immunol. Methods
– volume: 7
  start-page: 797
  year: 1978
  publication-title: Chem. Lett.
– volume: 12
  start-page: 5081
  year: 2010
  publication-title: Org. Lett.
– volume: 51
  start-page: 794
  year: 2003
  publication-title: Chem. Pharm. Bull.
– volume: 39
  start-page: 2337
  year: 1975
  publication-title: Agric. Biol. Chem.
– volume: 10
  start-page: 3547
  year: 1999
  publication-title: Tetrahedron: Asymmetry
– volume: 7
  start-page: 2766
  year: 2010
  publication-title: Chem. Biodiversity
– volume: 75
  start-page: 230
  year: 2012
  publication-title: J. Nat. Prod.
– volume: 58
  start-page: 1384
  year: 1995
  publication-title: J. Nat. Prod.
– volume: 31
  start-page: 769
  year: 2012
  publication-title: Junwu Xuebao
– volume: 75
  start-page: 142
  year: 2012
  publication-title: J. Nat. Prod.
– volume: 76
  start-page: 1229
  year: 2013
  publication-title: J. Nat. Prod.
– volume: 11
  start-page: 282
  year: 1983
  publication-title: J. Chem. Res., Synop.
– volume: 25
  start-page: 377
  year: 1987
  publication-title: Magn. Reson. Chem.
– volume: 90
  start-page: 220
  year: 2013
  publication-title: Fitoterapia
– volume: 102
  start-page: 7338
  year: 1998
  publication-title: J. Phys. Chem. B
– volume: 15
  start-page: 1037
  year: 1976
  publication-title: Phytochemistry
– volume: 66
  start-page: 539
  year: 2013
  publication-title: J. Antibiot.
– volume: 74
  start-page: 1303
  year: 2011
  publication-title: J. Nat. Prod.
– volume: 71
  start-page: 7103
  year: 2006
  publication-title: J. Org. Chem.
– volume: 21
  start-page: 3866
  year: 2013
  publication-title: Bioorg. Med. Chem.
– volume: 107
  start-page: 2524
  year: 2003
  publication-title: J. Phys. Chem. A
– volume: 53
  start-page: 1586
  year: 2009
  publication-title: Antimicrob. Agents Chemother.
– volume: 66
  start-page: 665
  year: 2005
  publication-title: Phytochemistry
– volume: 30
  start-page: 514
  year: 1982
  publication-title: Chem. Pharm. Bull.
– volume: 59
  start-page: 852
  year: 2010
  publication-title: Russ. Chem. Bull., Int. Ed.
– volume: 105
  start-page: 9972
  year: 1996
  publication-title: J. Chem. Phys.
– volume: 50
  start-page: 9843
  year: 2011
  publication-title: Angew. Chem., Int. Ed.
– volume: 41
  start-page: 2040
  year: 1993
  publication-title: Chem. Pharm. Bull.
– volume: 59
  start-page: 1102
  year: 1996
  publication-title: J. Nat. Prod.
– volume: 72
  start-page: 666
  year: 2009
  publication-title: J. Nat. Prod.
– volume: 37
  start-page: 2349
  year: 1984
  publication-title: Aust. J. Chem.
– volume: 8
  start-page: 646
  year: 1992
  publication-title: J. Chem. Soc., Chem. Commun.
– volume: 42
  start-page: 37
  year: 1978
  publication-title: Agric. Biol. Chem.
– volume: 65
  start-page: 2809
  year: 2004
  publication-title: Phytochemistry
– volume: 71
  start-page: 1089
  year: 1979
  publication-title: Mycologia
– volume: 54
  start-page: 6081
  year: 2013
  publication-title: Tetrahedron Lett.
– volume: 7
  start-page: 1529
  year: 1968
  publication-title: Phytochemistry
– volume: 55
  start-page: 304
  year: 2007
  publication-title: Chem. Pharm. Bull.
– volume: 409
  start-page: 3902
  year: 2011
  publication-title: Sci. Total Environ.
– volume: 65
  start-page: 7
  year: 2002
  publication-title: J. Nat. Prod.
– volume: 78
  start-page: 896
  year: 2013
  publication-title: Steroids
– volume: 83
  start-page: 1087
  year: 2012
  publication-title: Fitoterapia
– ident: e_1_2_1_46_2
  doi: 10.1016/j.phytochem.2004.08.020
– ident: e_1_2_1_47_2
  doi: 10.1016/0022-1759(83)90303-4
– ident: e_1_2_1_13_2
  doi: 10.1007/s11172-010-0173-5
– ident: e_1_2_1_34_2
  doi: 10.1021/np960542n
– ident: e_1_2_1_44_2
  doi: 10.1248/cpb.30.514
– ident: e_1_2_1_21_2
  doi: 10.1016/j.bmc.2013.04.004
– ident: e_1_2_1_30_2
  doi: 10.1016/j.phytochem.2004.12.031
– ident: e_1_2_1_45_2
  doi: 10.1039/c39920000646
– ident: e_1_2_1_28_2
  doi: 10.1021/jo0611059
– ident: e_1_2_1_3_2
  doi: 10.1021/np100909y
– ident: e_1_2_1_25_2
  doi: 10.3390/md10010234
– ident: e_1_2_1_39_2
  doi: 10.1021/np400465r
– ident: e_1_2_1_19_2
  doi: 10.1016/S0957-4166(99)00359-6
– ident: e_1_2_1_12_2
  doi: 10.1016/S0031-9422(00)88601-X
– ident: e_1_2_1_23_2
  doi: 10.1021/np800777f
– ident: e_1_2_1_48_2
  doi: 10.1128/AAC.00940-08
– ident: e_1_2_1_14_2
  doi: 10.1016/S0031-9422(01)00394-6
– volume: 31
  start-page: 769
  year: 2012
  ident: e_1_2_1_40_2
  publication-title: Junwu Xuebao
– ident: e_1_2_1_4_2
  doi: 10.1021/np2009362
– ident: e_1_2_1_51_2
  doi: 10.1021/jp0275802
– ident: e_1_2_1_54_2
  doi: 10.1002/chir.20733
– ident: e_1_2_1_15_2
  doi: 10.1271/bbb1961.42.37
– ident: e_1_2_1_31_2
  doi: 10.1071/CH9842349
– ident: e_1_2_1_42_2
  doi: 10.2307/3759302
– ident: e_1_2_1_41_2
  doi: 10.1002/cbdv.201000067
– ident: e_1_2_1_38_2
  doi: 10.1002/anie.201104488
– ident: e_1_2_1_26_2
  doi: 10.1002/mrc.1974
– ident: e_1_2_1_36_2
  doi: 10.1246/cl.1978.797
– ident: e_1_2_1_1_2
  doi: 10.1021/ol016737q
– ident: e_1_2_1_52_2
  doi: 10.1063/1.472829
– volume: 11
  start-page: 282
  year: 1983
  ident: e_1_2_1_16_2
  publication-title: J. Chem. Res., Synop.
– ident: e_1_2_1_43_2
  doi: 10.1248/cpb.41.2040
– ident: e_1_2_1_11_2
  doi: 10.1038/ja.2013.40
– ident: e_1_2_1_50_2
  doi: 10.1021/jp980939v
– ident: e_1_2_1_8_2
  doi: 10.1016/j.steroids.2013.05.007
– ident: e_1_2_1_24_2
  doi: 10.1248/cpb.55.304
– ident: e_1_2_1_33_2
  doi: 10.1021/np50123a008
– ident: e_1_2_1_37_2
  doi: 10.1021/np0102758
– ident: e_1_2_1_49_2
– ident: e_1_2_1_18_2
  doi: 10.1039/p19900002715
– ident: e_1_2_1_27_2
  doi: 10.1016/S0031-9422(00)84399-X
– ident: e_1_2_1_29_2
  doi: 10.1002/mrc.1260250502
– ident: e_1_2_1_17_2
  doi: 10.1271/bbb1961.39.2337
– ident: e_1_2_1_6_2
  doi: 10.1016/j.fitote.2013.08.002
– ident: e_1_2_1_20_2
  doi: 10.1021/np100059m
– ident: e_1_2_1_9_2
  doi: 10.1016/j.fitote.2012.05.002
– ident: e_1_2_1_53_2
  doi: 10.1021/j100007a062
– ident: e_1_2_1_5_2
  doi: 10.1021/np200614h
– ident: e_1_2_1_7_2
  doi: 10.1021/np200769q
– ident: e_1_2_1_22_2
  doi: 10.1016/j.tetlet.2013.08.137
– ident: e_1_2_1_32_2
  doi: 10.1016/j.scitotenv.2011.06.010
– ident: e_1_2_1_35_2
  doi: 10.1002/jlac.197819780811
– ident: e_1_2_1_2_2
  doi: 10.1021/ol102168z
– ident: e_1_2_1_10_2
  doi: 10.1248/cpb.51.794
SSID ssj0028808
Score 2.3501952
Snippet A chemical investigation of the endolichenic fungus Aspergillus versicolor (125a), which was found in the lichen Lobaria quercizans, resulted in the isolation...
A chemical investigation of the endolichenic fungus Aspergillus versicolor (125a), which was found in the lichen Lobaria quercizans , resulted in the isolation...
SourceID proquest
pubmed
crossref
wiley
istex
SourceType Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 575
SubjectTerms Acids
Antifungal activity
Antifungal Agents - chemistry
Antifungal Agents - isolation & purification
Antifungal Agents - pharmacology
Antineoplastic Agents, Phytogenic - chemistry
Antineoplastic Agents, Phytogenic - pharmacology
Aspergillus - chemistry
Aspergillus - metabolism
Aspergillus versicolor
Bioassays
Bisabolane sesquiterpenoid
Candida albicans
Candida albicans - drug effects
Cell Line, Tumor - drug effects
Circular Dichroism
Cytotoxic activity
Dichroism
Drug Evaluation, Preclinical - methods
Endolichenic fungus
Ethers
Fungi
Humans
Lichens - microbiology
Lobaria quercizans
Magnetic Resonance Spectroscopy
Metabolites
Molecular Structure
Phenyl Ethers - chemistry
Phenyl Ethers - pharmacology
Pyrogallol
Secondary Metabolism
Secondary metabolites
Sesquiterpenes - chemistry
Sesquiterpenes - isolation & purification
Sesquiterpenoids
Structure-Activity Relationship
Tumor cell lines
Title Identification and Biological Evaluation of Secondary Metabolites from the Endolichenic Fungus Aspergillus versicolor
URI https://api.istex.fr/ark:/67375/WNG-R8GNX45M-V/fulltext.pdf
https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fcbdv.201400146
https://www.ncbi.nlm.nih.gov/pubmed/25879502
https://www.proquest.com/docview/1673369273
https://www.proquest.com/docview/2691615105
https://www.proquest.com/docview/1674217748
https://www.proquest.com/docview/1680462714
Volume 12
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9QwELZQKyQuQHkGCjISglPaxOvYzrG0u62QuodCy94svwJVV1m0u6lafj0eO2tYVECCWyLbkR8z42-cmc8Iva6VKEhNeW6agcop0TxXptS580qpK2aJiwGyY3Z0St9PqslPWfyRHyIduIFmBHsNCq70YvcHaajR9hJCsyigfODchoAtQEUniT-KeOEMuXB-G89LwcmKtbEgu-vN13alTZjgq5sg5zqCDVvQ6B5Sq87HyJOLnW6pd8y3X3gd_2d099HdHp_ivShQW-iWax-g2_HGyuuHqIuJvU1_0odVa3EshMXGw8QdjmcN_gDOtvV9wMdu6YUN0p0XGBJasIedeNhaICX-4tpzg0fe6HQLvAfE5Z_Pp1P_HAJGgFR7_gidjoYf94_y_uaG3FBOWG5r7ax22nCjC-udFmKbgbGiEtbWjmhhy5oyqwg1qjCEKacGLFgfDxg4N4PHaKOdte4pwtR4mwPZtUIJCv4Va6xgXFHTiEqXNEP5auWk6WnN4XaNqYyEzETCVMo0lRl6m-p_jYQev635JghCqqbmFxAGxyv5aXwoT8TheEKrY3mWoe2VpMjeAixkyYBosvbo8MZiwmrA2h7dZuhVKvaqDf9rVOtmXfgE9R4jp-JPdQSkF3OYiCdRSFN_SQU3yRckQySI2l_GK_ffHZylt2f_0ug5uuOfqxjZtI02lvPOvfCgbalfBsX8Dj-xOCE
linkProvider Wiley-Blackwell
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9QwELagFYIL70eggJEQnNImXsd2jqXsdoHuHkpberP8ClRdZdHuBgG_Ho-dBC0qIMEtiZ3IcWbG3zgz3yD0vFQiIyXlqakGKqVE81SZXKfOK6UumCUuBshO2fiYvj0tumhCyIWJ_BD9hhtoRrDXoOCwIb3zkzXUaPsFYrMowHx2GW1CWe_gVR32DFLEi2fIhvMLeZoLTjrexozsrN-_ti5twhR_vQh0rmPYsAiNbiDdDT_GnpxvNyu9bb7_wuz4X-93E11vISrejTJ1C11y9W10JRat_HYHNTG3t2o3-7CqLY6N8L3xsKcPx_MKvwd_2_pB4IlbeXmDjOclhpwW7JEnHtYWeIk_ufrM4JG3O80S7wJ3-cez2cwfh5gR4NVe3EXHo-HR3jhtizekhnLCUltqZ7XThhudWe-3EFsNjBWFsLZ0RAubl5RZRahRmSFMOTVgwQB5zMC5GdxDG_W8dg8QpsabHUiwFUpQcLFYZQXjippKFDqnCUq7TydNy2wOBTZmMnIyEwlTKfupTNDLvv_nyOnx254vgiT03dTiHCLheCE_TPflodifntJiIk8StNWJimyNwFLmDLgmSw8QL2wmrAS47QFugp71zV674ZeNqt28CY-g3mnkVPypj4AMYw4TcT9KaT9eUkAx-YwkiARZ-8v7yr1Xr0_6s4f_ctNTdHV8NDmQB2-m7x6ha_56EQOdttDGatG4xx7DrfSToKU_AKyvPDw
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1bb9MwFLZgE4gX7pfAACMheMqWuI7tPI613bisQoONvlm-ZZtWpVPbIODX42OngaIBErwlsRP5cs7xd5xzPiP0vFQiIyXlqal6KqVE81SZXKfOK6UumCUuBsiO2N4hfTMuxj9l8Ud-iG7DDTQj2GtQ8HNbbf0gDTXafobQLAoon11G65RlAuS6f9ARSBEvnSEZzq_jaS44WdI2ZmRr9f2VZWkdRvjLRZhzFcKGNWh4A6ll62Poydlms9Cb5tsvxI7_072b6HoLUPF2lKhb6JKrb6Mr8cjKr3dQEzN7q3arD6va4lgIs40HHXk4nlb4A3jb1rcB77uFlzbId55jyGjBHnfiQW2BlfjE1acGD73VaeZ4G5jLj08nE38dIkaAVXt2Fx0OBx939tL26IbUUE5YakvtrHbacKMz670WYquesaIQ1paOaGHzkjKrCDUqM4Qpp3osmB-PGDg3vXtorZ7W7gHC1HijA-m1QgkKDharrGBcUVOJQuc0Qely5qRpec3heI2JjIzMRMJQym4oE_Syq38eGT1-W_NFEISumpqdQRwcL-Sn0a48ELujMS325VGCNpaSIlsTMJc5A6bJ0sPDC4sJKwFse3iboGddsddt-GGjajdtwieodxk5FX-qIyC_mMNA3I9C2rWXFHCUfEYSRIKo_aW_cudV_6i7e_gvLz1FV9_3h_Ld69HbR-iaf1zEKKcNtLaYNe6xB3AL_STo6HffxTr0
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Identification+and+Biological+Evaluation+of+Secondary+Metabolites+from+the+Endolichenic+Fungus+Aspergillus+versicolor&rft.jtitle=Chemistry+%26+biodiversity&rft.au=Li%2C+Xiao%E2%80%90Bin&rft.au=Zhou%2C+Yan%E2%80%90Hui&rft.au=Zhu%2C+Rong%E2%80%90Xiu&rft.au=Chang%2C+Wen%E2%80%90Qiang&rft.date=2015-04-01&rft.issn=1612-1872&rft.eissn=1612-1880&rft.volume=12&rft.issue=4&rft.spage=575&rft.epage=592&rft_id=info:doi/10.1002%2Fcbdv.201400146&rft.externalDBID=n%2Fa&rft.externalDocID=10_1002_cbdv_201400146
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1612-1872&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1612-1872&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1612-1872&client=summon