Quercetin alleviates microglial-induced inflammation after traumatic brain injury via the PGC-1α/Nrf2 pathway dependent on HDAC3 inhibition - Zhai, Xiaofu; Wang, Ziyu; Gao, Juemin (Brain research bulletin, 2024)
Keywords: Animals; Apoptosis - drug effects; Brain Injuries, Traumatic - drug therapy; Brain Injuries, Traumatic - metabolism; Brain Injuries, Traumatic - pathology; Disease Models, Animal; HDAC3; Histone Deacetylases - metabolism; Inflammation; Inflammation - drug therapy; Inflammation - metabolism; Male; Mice; Mice, Inbred C57BL; Microglia - drug effects; Microglia - metabolism; Neuroinflammatory Diseases - drug therapy; Neuroinflammatory Diseases - metabolism; Neurons - drug effects; Neurons - metabolism; Neurons - pathology; Neuroprotective Agents - pharmacology; NF-E2-Related Factor 2 - metabolism; Nrf2; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - metabolism; PGC-1α; Quercetin; Quercetin - pharmacology; Signal Transduction - drug effects; Traumatic brain injury; Inflammation; PGC-1α; Traumatic brain injury; HDAC3; Nrf2; Quercetin