Chronic PFOS Exposure Disrupts Thyroid Structure and Function in Zebrafish

• Published in: Bulletin of environmental contamination and toxicology Vol. 101; no. 1; pp. 75 - 79
• Main Authors: Chen, Jiangfei, Zheng, Lidan, Tian, Linjie, Wang, Nengzhuang, Lei, Lei, Wang, Yanbo, Dong, Qiaoxiang, Huang, Changjiang, Yang, Dongren
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.07.2018; Springer Nature B.V
• Subjects: Alkanesulfonic Acids - toxicity; Animals; Aquatic organisms; Aquatic Pollution; cell structures; Chronic toxicity; Cytology; Danio rerio; Earth and Environmental Science; Ecotoxicology; Embryo, Nonmammalian - drug effects; Embryo, Nonmammalian - physiology; Endocrine disruptors; Endocrine Disruptors - toxicity; endocrine-disrupting chemicals; Environment; Environmental Chemistry; Environmental Health; Exposure; Fertilization; Fluorocarbons - toxicity; Gene expression; humans; Perfluorooctane sulfonic acid; Pollution; screening; Soil Science & Conservation; Structure-function relationships; Sulfonic acid; Thyroid; thyroid function; Thyroid gland; Thyroid Gland - drug effects; Thyroid Gland - physiology; thyroid hormones; Thyroxine; Toxicity; Triiodothyronine; Waste Water Technology; Water Management; Water Pollution Control; Wildlife; Zebrafish; Zebrafish; Thyroid hormone; Gene expression; Thyroid morphology; PFOS

Perfluorooctane sulfonic acid (PFOS), as a potential endocrine disrupting chemical, is widely detected in the environment, wildlife and human. Currently few studies have documented the effects of chronic PFOS exposure on thyroid in aquatic organisms and the underlying mechanisms are largely unknown....