A Peptide-Nucleic Acid Targeting miR-335-5p Enhances Expression of Cystic Fibrosis Transmembrane Conductance Regulator ( CFTR ) Gene with the Possible Involvement of the CFTR Scaffolding Protein NHERF1

• Published in: Biomedicines Vol. 9; no. 2; p. 117
• Main Authors: Tamanini, Anna, Fabbri, Enrica, Jakova, Tiziana, Gasparello, Jessica, Manicardi, Alex, Corradini, Roberto, Finotti, Alessia, Borgatti, Monica, Lampronti, Ilaria, Munari, Silvia, Dechecchi, Maria Cristina, Cabrini, Giulio, Gambari, Roberto
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI 26.01.2021; MDPI AG
• Subjects: cystic fibrosis; delivery; microRNAs; miR-335-5p; miRNA targeting; peptide nucleic acids; microRNAs; delivery; NHERF1; miR-335-5p; miRNA targeting; cystic fibrosis; CFTR; peptide nucleic acids

(1) Background: Up-regulation of the Cystic Fibrosis Transmembrane Conductance Regulator gene ( ) might be of great relevance for the development of therapeutic protocols for cystic fibrosis (CF). MicroRNAs are deeply involved in the regulation of CFTR and scaffolding proteins (such as NHERF1, NHERF...