Clinical and microbiological effects of ozone nano-bubble water irrigation as an adjunct to mechanical subgingival debridement in periodontitis patients in a randomized controlled trial

• Published in: Clinical oral investigations Vol. 17; no. 2; pp. 379 - 388
• Main Authors: Hayakumo, Sae, Arakawa, Shinichi, Mano, Yoshihiro, Izumi, Yuichi
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.03.2013; Springer Nature B.V
• Subjects: Adult; Aged; Anti-Infective Agents, Local - administration & dosage; Anti-Infective Agents, Local - therapeutic use; Bacterial Load - drug effects; Bacteroides - drug effects; Bacteroides - isolation & purification; Chronic Periodontitis - microbiology; Chronic Periodontitis - therapy; Dental Plaque - microbiology; Dental Plaque - therapy; Dentistry; Female; Follow-Up Studies; Humans; Male; Medicine; Microbubbles; Middle Aged; Nanospheres; Original Article; Ozone - administration & dosage; Ozone - therapeutic use; Periodontal Attachment Loss - microbiology; Periodontal Attachment Loss - therapy; Periodontal Debridement - methods; Periodontal Index; Periodontal Pocket - microbiology; Periodontal Pocket - therapy; Placebos; Porphyromonas gingivalis - drug effects; Porphyromonas gingivalis - isolation & purification; Single-Blind Method; Subgingival Curettage - methods; Therapeutic Irrigation - methods; Irrigation; Subgingival debridement; Periodontitis; Adjunctive antimicrobial agents; Ozone nano-bubble water

Aim Ozone nano-bubble water (NBW3) seems to be suitable as an adjunct to periodontal treatment owing to its potent antimicrobial effects, high level of safety, and long storage stability. The aim of the present study was to evaluate the clinical and microbiological effects of NBW3 irrigation as an a...