Improved cognition and preserved hippocampal fractional anisotropy in subjects undergoing carotid endarterectomy “CEA preserves cognition & hippocampal structure”

• Published in: Journal of stroke and cerebrovascular diseases Vol. 33; no. 11; p. 107926
• Main Authors: Bernstein, Adam, Arias, Juan C., Howell, Caronae, French, Scott, Guzman, Gloria, Bruck, Denise, Berman, Scott, Leon, Luis, Pacanowski, John, Tan, Tze-Woei, Altbach, Maria, Trouard, Theodore, Weinkauf, Craig
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2024
• Subjects: Aged; Anisotropy; Asymptomatic Diseases; Carotid artery atherosclerosis; Carotid Stenosis - complications; Carotid Stenosis - diagnostic imaging; Carotid Stenosis - physiopathology; Carotid Stenosis - surgery; Cognition; Diffusion Magnetic Resonance Imaging; Endarterectomy, Carotid - adverse effects; Female; Fractional anisotropy; Hippocampus - diagnostic imaging; Hippocampus - pathology; Humans; Male; Mental Status and Dementia Tests; Middle Aged; Neurocognitive assessment; Predictive Value of Tests; Prospective Studies; Recovery of Function; Severity of Illness Index; Time Factors; Treatment Outcome; Carotid artery atherosclerosis; Fractional anisotropy; Neurocognitive assessment; Diffusion magnetic resonance imaging

A growing body of data indicates that extracranial carotid artery disease (ECAD) can contribute to cognitive impairment. However, there have been mixed reports regarding the benefit of carotid endarterectomy (CEA) as it relates to preserving cognitive function. In this work, diffusion magnetic reson...