Comparison of delta-tocotrienol and alpha-tocopherol effects on hepatic steatosis and inflammatory biomarkers in patients with non-alcoholic fatty liver disease: A randomized double-blind active-controlled trial

• Published in: Complementary therapies in medicine Vol. 70; p. 102866
• Main Authors: Pervez, Muhammad Amjad, Khan, Dilshad Ahmed, Mirza, Shakeel Ahmed, Slehria, Atiq Ur Rehman, Nisar, Uzma, Aamir, Mohammad
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.11.2022; Elsevier Limited; Elsevier
• Subjects: Adipocytes; Adiponectin; Apoptosis; Armed forces; Biochemical analysis; Biomarkers; Body weight; Cholesterol; Clinical trials; Computed tomography; Cytokeratin; Dietary supplements; Double-blind studies; Enzymes; Fatty liver; Fatty liver index; Inflammation; Inflammatory biomarkers; Insulin; Insulin resistance; Interleukin 6; Interleukins; Laboratories; Leptin; Liver; Liver diseases; Liver-to-spleen attenuation ratio; Non-alcoholic fatty liver disease; Nutrition research; Oxidation resistance; Oxidative stress; Patients; Steatosis; Tocopherol; Triglycerides; Tumor necrosis factor-TNF; Tumor necrosis factor-α; Vitamin E; Weight reduction; α-tocopherol; δ-tocotrienol; Rawalpindi Pakistan; United States > US; Pakistan; Inflammatory biomarkers; Fatty liver index; δ-tocotrienol; Liver-to-spleen attenuation ratio; Non-alcoholic fatty liver disease; α-tocopherol

We aimed to compare the efficacy of δ-tocotrienol with α-tocopherol in the treatment of patients with non-alcoholic fatty liver disease (NAFLD). This study was a double-blinded, active-controlled trial. The patients with NAFLD were randomly assigned to receive either δ-tocotrienol 300 mg or α-tocoph...