Hepatic Fat Content Is Associated with Fasting-Induced Fibroblast Growth Factor 21 Secretion in Mice Fed Soy Proteins

• Published in: Journal of Nutritional Science and Vitaminology Vol. 65; no. 6; pp. 515 - 525
• Main Authors: TANIGUCHI, Hirokazu, AKIYAMA, Nao, ISHIHARA, Kengo
• Format: Journal Article
• Language: English
• Published: Japan Center for Academic Publications Japan 01.01.2019
• Subjects: central obesity; fatty liver; FGF21; high-fat high-sucrose diet; β-conglycinin; central obesity; β-conglycinin; high-fat high-sucrose diet; fatty liver; FGF21

Previous studies suggest that circulating fibroblast growth factor 21 (FGF21) levels are elevated in patients with fatty liver, while fasting-induced secretion of FGF21 is lower in obese patients. It has been reported that soy protein prevents hepatic fat accumulation and induces FGF21 secretion. Th...