Mitochondrial dynamics and mitochondrial quality control

• Published in: Redox biology Vol. 4; no. C; pp. 6 - 13
• Main Authors: Ni, Hong-Min, Williams, Jessica A., Ding, Wen-Xing
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier 01.04.2015
• Subjects: Animals; Autophagy; Cytoskeleton - genetics; Graphical Review; Homeostasis; Humans; Lysosomes - metabolism; Mammals; Mitochondria - genetics; Mitochondria - metabolism; Mitochondrial Degradation - genetics; Mitochondrial Dynamics - genetics; Mitochondrial spheroids; Mitophagy; Parkin; Mitophagy; Mitochondrial spheroids; Autophagy; Parkin

Mitochondria are cellular energy powerhouses that play important roles in maintaining cell survival, cell death and cellular metabolic homeostasis. Timely removal of damaged mitochondria via autophagy (mitophagy) is thus critical for cellular homeostasis and function. Mitochondria are reticular orga...