Multivariate classification of social anxiety disorder using whole brain functional connectivity

• Published in: Brain Structure and Function Vol. 220; no. 1; pp. 101 - 115
• Main Authors: Liu, Feng, Guo, Wenbin, Fouche, Jean-Paul, Wang, Yifeng, Wang, Wenqin, Ding, Jurong, Zeng, Ling, Qiu, Changjian, Gong, Qiyong, Zhang, Wei, Chen, Huafu
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.01.2015; Springer Nature B.V
• Subjects: Adolescent; Adult; Anatomy & physiology; Anxiety; Anxiety Disorders - classification; Anxiety Disorders - pathology; Biomedical and Life Sciences; Biomedicine; Brain; Brain - blood supply; Brain - pathology; Brain Mapping; Case-Control Studies; Cell Biology; Female; Humans; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Male; Multivariate Analysis; Neural Pathways - blood supply; Neural Pathways - pathology; Neurology; Neuropsychology; Neurosciences; NMR; Nonlinear Dynamics; Nuclear magnetic resonance; Original Article; Psychiatric Status Rating Scales; Regression Analysis; ROC Curve; Social Behavior; Support Vector Machine; Young Adult; Functional connectivity; Resting-state fMRI; Consensus features; Multivariate pattern analysis; Support vector machine; Social anxiety disorder/social phobia

Recent research has shown that social anxiety disorder (SAD) is accompanied by abnormalities in brain functional connections. However, these findings are based on group comparisons, and, therefore, little is known about whether functional connections could be used in the diagnosis of an individual p...