Vitamin D deficiency associates with γ-tocopherol and quadriceps weakness but not inflammatory cytokines in subjects with knee osteoarthritis

• Published in: Redox biology Vol. 2; no. C; pp. 466 - 474
• Main Authors: Barker, Tyler, Henriksen, Vanessa T., Rogers, Victoria E., Aguirre, Dale, Trawick, Roy H., Lynn Rasmussen, G., Momberger, Nathan G.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier 01.01.2014
• Subjects: Adult; Cytokines; Female; gamma-Tocopherol - blood; Humans; Male; Middle Aged; Muscle strength; Muscle Weakness - physiopathology; Osteoarthritis, Knee - complications; Osteoarthritis, Knee - immunology; Osteoarthritis, Knee - physiopathology; Quadriceps Muscle - physiopathology; Research Paper; Tumor Necrosis Factor-alpha - blood; Vitamin D; Vitamin D - blood; Vitamin D Deficiency - complications; Vitamin D Deficiency - immunology; Vitamin D Deficiency - physiopathology; Vitamin E; Muscle strength; Cytokines; Vitamin D; Vitamin E

Knee osteoarthritis (OA) is a degenerative joint condition and a leading cause of physical disability in the United States. Quadriceps weakness and inflammatory cytokines contribute to the pathogenesis of knee OA, and both of which, increase with vitamin D deficiency. Other micronutrients, such as v...