GPR119 agonists for the treatment of type 2 diabetes

• Published in: Expert opinion on therapeutic patents Vol. 19; no. 10; p. 1339
• Main Authors: Jones, Robert M, Leonard, James N, Buzard, Daniel J, Lehmann, Juerg
• Format: Journal Article
• Language: English
• Published: England 01.10.2009
• Subjects: Animals; Blood Glucose - drug effects; Diabetes Mellitus, Type 2 - drug therapy; Diabetes Mellitus, Type 2 - metabolism; Drug Design; Drug Therapy, Combination; Humans; Hypoglycemic Agents - chemistry; Hypoglycemic Agents - therapeutic use; Incretins - metabolism; Insulin - metabolism; Molecular Structure; Patents as Topic; Receptors, G-Protein-Coupled - agonists; Receptors, G-Protein-Coupled - metabolism; Signal Transduction - drug effects; Structure-Activity Relationship; Treatment Outcome

Diabetes is a chronic disease that occurs when the pancreas does not produce enough insulin, or when the body cannot effectively use the insulin it produces. Hyperglycemia, or raised blood sugar, is a common effect of uncontrolled diabetes and over time leads to serious damage to many of the body�...