A Comparison of Assay Performance Measures in Screening Assays: Signal Window, Z′ Factor, and Assay Variability Ratio

• Published in: Journal of biomolecular screening Vol. 11; no. 3; pp. 247 - 252
• Main Authors: Iversen, Philip W., Eastwood, Brian J., Sittampalam, G. Sitta, Cox, Karen L.
• Format: Journal Article
• Language: English
• Published: United States 01.04.2006
• Subjects: Animals; Cell Proliferation; Lung - cytology; Lung - drug effects; Mink; Models, Theoretical

In this article, the authors compare the assay performance measures, signal window, Z' factor, and assay variability ratio. They examine their mathematical formulae for similarities and differences, describe their statistical sampling properties using the results of a computer simulation, and i...