Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1 - Lehrbach, Nicolas J; Ruvkun, Gary (eLife, 2016)
Keywords: Animals; Aspartic Acid Proteases - metabolism; Aspartic endopeptidase; aspartic protease; Bacteria; Caenorhabditis elegans - enzymology; Caenorhabditis elegans - metabolism; Caenorhabditis elegans Proteins - metabolism; Cancer; Cell Biology; Developmental Biology and Stem Cells; DNA-Binding Proteins - metabolism; E coli; ER traffic; Gene Expression Regulation; Genes; Homeostasis; Mutation; N-glycanase; Nematodes; peptide N-glycanase; proteasome; Proteasome Endopeptidase Complex - metabolism; Proteasomes; Protein interaction; Proteins; Proteolysis; SKN-1A/Nrf1; Software; Transcription activation; Transcription factors; Transcription Factors - metabolism; proteasome; stem cells; C. elegans; cell biology; ER traffic; developmental biology; SKN-1A/Nrf1; peptide N-glycanase; aspartic protease