Recombinant human interferon gamma (Gamma Immunex) in treatment of atopic dermatitis

• Published in: Clinical and experimental medicine Vol. 12; no. 4; pp. 241 - 245
• Main Authors: Panahi, Yunes, Davoudi, Seyyed Masoud, Madanchi, Nima, Abolhasani, Ehsan
• Format: Journal Article
• Language: English
• Published: Milan Springer Milan 01.12.2012; Springer Nature B.V
• Subjects: Atopic dermatitis; Cytokines; Dermatitis; Dermatitis, Atopic - drug therapy; Dermatitis, Atopic - pathology; Dermatology; gamma -Interferon; Hematology; Humans; Immunoglobulin E; Immunoglobulin E - blood; Immunotherapy - methods; Inflammatory diseases; Interferon; Interferon-gamma - administration & dosage; Interleukin 4; Interleukin 6; Interleukin-4 - blood; Interleukin-6 - blood; Internal Medicine; Iran; Medicine; Medicine & Public Health; Oncology; Original Article; Pharmaceuticals; Pharmacology; pruritus; Quality of Life; Recombinant Proteins - administration & dosage; Scaling; Serum levels; Severity of Illness Index; Skin diseases; Treatment Outcome; Iran; Atopic dermatitis; Interleukin; Gamma interferon; Quality of life

Atopic dermatitis (AD) is a chronic, inflammatory skin disease which is characterized by severe pruritus and affects patients’ quality of life. In recent years gamma interferon (IFN-gamma) has been accepted as a novel treatment for severe AD, however, its mechanism of action is not clearly identifie...