Diastolic Dysfunction in Individuals With Human Immunodeficiency Virus Infection: Literature Review, Rationale and Design of the Characterizing Heart Function on Antiretroviral Therapy (CHART) Study

• Published in: Journal of cardiac failure Vol. 24; no. 4; pp. 255 - 265
• Main Authors: Butler, Javed, Kalogeropoulos, Andreas P., Anstrom, Kevin J., Hsue, Priscilla Y., Kim, Raymond J., Scherzer, Rebecca, Shah, Sanjiv J., Shah, Svati H., Velazquez, Eric J., Hernandez, Adrian F., Desvigne-Nickens, Patrice, Braunwald, Eugene
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2018
• Subjects: Anti-Retroviral Agents - therapeutic use; diastolic dysfunction; Global Health; heart failure; Heart Failure, Diastolic - epidemiology; Heart Failure, Diastolic - etiology; Heart Failure, Diastolic - physiopathology; HIV; HIV Infections - complications; HIV Infections - drug therapy; Human immunodeficiency virus; Humans; Incidence; pathophysiology; Prognosis; Stroke Volume - physiology; Ventricular Function, Left - physiology; diastolic dysfunction; heart failure; Human immunodeficiency virus; pathophysiology

Antiretroviral therapy (ART) has been associated with a shift in the epidemiology of human immunodeficiency virus (HIV)–associated cardiomyopathy from a phenotype of primarily left ventricular (LV) systolic dysfunction to LV diastolic dysfunction (DD). Patients with HIV receiving ART have higher rat...