Circulating Red Cell—derived Microparticles in Human Malaria

• Published in: The Journal of infectious diseases Vol. 203; no. 5; pp. 700 - 706
• Main Authors: Nantakomol, Duangdao, Dondorp, Arjen M., Krudsood, Srivicha, Udomsangpetch, Rachanee, Pattanapanyasat, Kovit, Combes, Valery, Grau, Georges E., White, Nicholas J., Viriyavejakul, Parnpen, Day, Nicholas P.J., Chotivanich, Kesinee
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.03.2011
• Subjects: Antimalarials - pharmacology; Biological and medical sciences; Blood; Blood plasma; Case-Control Studies; Cell-Derived Microparticles - drug effects; Cell-Derived Microparticles - parasitology; Cytometry; Erythrocytes; Falciparum malaria; Fundamental and applied biological sciences. Psychology; Human protozoal diseases; Humans; Infections; Infectious diseases; Major and Brief Reports; Malaria; Malaria - blood; Malaria - diagnosis; Malaria - drug therapy; Malaria - parasitology; Medical sciences; Microbiology; Parasites; Parasitic diseases; Parasitism; Plasmodium - drug effects; Plasmodium - isolation & purification; Protozoal diseases; Thailand; Tropical medicine; Thailand; Human; Infection; Blood cell; Protozoal disease; Malaria; Red blood cell; Parasitosis

In patients with falciparum malaria, plasma concentrations of cell-derived microparticles correlate with disease severity. Using flow cytometry, we quantified red blood cell—derived microparticles (RMPs) in patients with malaria and identified the source and the factors associated with production. R...