Increased expression of ACE2, the SARS-CoV-2 entry receptor, in alveolar and bronchial epithelium of smokers and COPD subjects - Jacobs, Merel; Van Eeckhoutte, Hannelore P.; Wijnant, Sara R.A.; Janssens, Wim; Joos, Guy F.; Brusselle, Guy G.; Bracke, Ken R. (The European respiratory journal, 2020)
Keywords: Agora; Angiotensin-Converting Enzyme 2; Belgium; Betacoronavirus - metabolism; Biomarkers - blood; Biopsy, Needle; Cross-Sectional Studies; Female; Humans; Immunohistochemistry; In Vitro Techniques; Linear Models; Male; Multivariate Analysis; Peptidyl-Dipeptidase A - metabolism; Pulmonary Disease, Chronic Obstructive - blood; Pulmonary Disease, Chronic Obstructive - epidemiology; Pulmonary Disease, Chronic Obstructive - pathology; Real-Time Polymerase Chain Reaction - methods; Respiratory Mucosa - metabolism; Respiratory Mucosa - pathology; RNA, Messenger - blood; SARS-CoV-2; Sensitivity and Specificity; Smoking - blood; Smoking - epidemiology; Specimen Handling; Statistics, Nonparametric; Belgium