Zebrafish as a pharmacological tool: the how, why and when

• Published in: Current opinion in pharmacology Vol. 4; no. 5; pp. 504 - 512
• Main Author: Goldsmith, Paul
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.10.2004
• Subjects: Animals; Disease Models, Animal; Drug Evaluation, Preclinical - methods; Mammals - physiology; Species Specificity; Zebrafish - embryology; Zebrafish - genetics; Zebrafish - physiology; ARMD; HERG

Zebrafish combine the relevance of a vertebrate with the scalability of an invertebrate. They can live in 96-well plate format and readily absorb chemicals from the water. These features have stimulated the use of zebrafish by medical researchers to model human disease and then assess the action of...