Pathways of the Maillard reaction under physiological conditions

• Published in: Glycoconjugate journal Vol. 33; no. 4; pp. 499 - 512
• Main Authors: Henning, Christian, Glomb, Marcus A.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.08.2016; Springer Nature B.V
• Subjects: Alzheimer Disease - metabolism; Amino acids; Animals; Atherosclerosis - metabolism; Biochemistry; Biomedical and Life Sciences; Carbohydrates; Cataract - metabolism; Diabetes Mellitus - metabolism; Glycation End Products, Advanced - metabolism; Humans; Life Sciences; Maillard Reaction; Oxidative stress; Pathology; Review; Uremia - metabolism; Oxidative stress; Fragmentation pathways; β-Dicarbonyl cleavage; Amide-AGEs; Maillard reaction; Carbohydrate chemistry; Advanced glycation endproducts AGE

Initially investigated as a color formation process in thermally treated foods, nowadays, the relevance of the Maillard reaction in vivo is generally accepted. Many chronic and age-related diseases such as diabetes, uremia, atherosclerosis, cataractogenesis and Alzheimer’s disease are associated wit...