Social anxiety symptoms and their relationship with suicidal ideation and depressive symptoms in adolescents: A prospective study

Background Social anxiety disorder typically emerges in adolescence and its symptoms often co‐occur with depression and suicidal ideation. It is important to understand whether social anxiety symptoms precede depression and suicidal ideation in youth. This study aimed to investigate the temporal ass...

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Published inJCPP advances Vol. 5; no. 1; pp. e12249 - n/a
Main Authors Chiu, Kenny, Stringaris, Argyris, Leigh, Eleanor
Format Journal Article
LanguageEnglish
Published United States John Wiley and Sons Inc 01.03.2025
Wiley
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ISSN2692-9384
2692-9384
DOI10.1002/jcv2.12249

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Abstract Background Social anxiety disorder typically emerges in adolescence and its symptoms often co‐occur with depression and suicidal ideation. It is important to understand whether social anxiety symptoms precede depression and suicidal ideation in youth. This study aimed to investigate the temporal associations between baseline social anxiety and later suicidal ideation and depressive symptoms in a community youth sample. Methods The Wellcome Trust NSPN (Neuroscience in Psychiatry Network) study recruited 2397 youth aged 14–24 in the United Kingdom to participate in a prospective observational study. Participants were assessed for symptoms of social anxiety, generalised anxiety, depression and suicidal ideation at baseline, 1‐year follow‐up, and 2‐year follow‐up. We conducted multiple linear regression analyses and mediation analyses to examine whether baseline social anxiety was associated with 2‐year suicidal ideation and depressive symptoms (excluding suicide‐related items), and whether these associations were mediated by 1‐year depressive symptoms. The study was preregistered on the Open Science Framework. Results Results from multiple linear regression analyses indicated that baseline social anxiety symptoms were associated with 2‐year suicidal ideation (β = 0.07, p < 0.05, 95% CI [0.02, 0.12]) and 2‐year depressive symptoms (β = 0.08, p < 0.05, 95% CI [0.02, 0.13]), after controlling for baseline predicted variable. Furthermore, 1‐year depressive symptoms significantly mediated the relationship between baseline social anxiety symptoms and 2‐year suicidal ideation (β = 0.04, 95% CI [0.02, 0.05]), and the relationship between baseline social anxiety symptoms and 2‐year depressive symptoms (β = 0.06, 95% CI [0.03, 0.08]) after adjusting for age, sex, and other covariates. Conclusions We found evidence that baseline social anxiety symptoms were associated with 2‐year suicidal ideation and 2‐year depressive symptoms via 1‐year depressive symptoms in non‐clinical adolescents. These results may have important implications for targeted psychological interventions.
AbstractList Social anxiety disorder typically emerges in adolescence and its symptoms often co-occur with depression and suicidal ideation. It is important to understand whether social anxiety symptoms precede depression and suicidal ideation in youth. This study aimed to investigate the temporal associations between baseline social anxiety and later suicidal ideation and depressive symptoms in a community youth sample.BackgroundSocial anxiety disorder typically emerges in adolescence and its symptoms often co-occur with depression and suicidal ideation. It is important to understand whether social anxiety symptoms precede depression and suicidal ideation in youth. This study aimed to investigate the temporal associations between baseline social anxiety and later suicidal ideation and depressive symptoms in a community youth sample.The Wellcome Trust NSPN (Neuroscience in Psychiatry Network) study recruited 2397 youth aged 14-24 in the United Kingdom to participate in a prospective observational study. Participants were assessed for symptoms of social anxiety, generalised anxiety, depression and suicidal ideation at baseline, 1-year follow-up, and 2-year follow-up. We conducted multiple linear regression analyses and mediation analyses to examine whether baseline social anxiety was associated with 2-year suicidal ideation and depressive symptoms (excluding suicide-related items), and whether these associations were mediated by 1-year depressive symptoms. The study was preregistered on the Open Science Framework.MethodsThe Wellcome Trust NSPN (Neuroscience in Psychiatry Network) study recruited 2397 youth aged 14-24 in the United Kingdom to participate in a prospective observational study. Participants were assessed for symptoms of social anxiety, generalised anxiety, depression and suicidal ideation at baseline, 1-year follow-up, and 2-year follow-up. We conducted multiple linear regression analyses and mediation analyses to examine whether baseline social anxiety was associated with 2-year suicidal ideation and depressive symptoms (excluding suicide-related items), and whether these associations were mediated by 1-year depressive symptoms. The study was preregistered on the Open Science Framework.Results from multiple linear regression analyses indicated that baseline social anxiety symptoms were associated with 2-year suicidal ideation (β = 0.07, p < 0.05, 95% CI [0.02, 0.12]) and 2-year depressive symptoms (β = 0.08, p < 0.05, 95% CI [0.02, 0.13]), after controlling for baseline predicted variable. Furthermore, 1-year depressive symptoms significantly mediated the relationship between baseline social anxiety symptoms and 2-year suicidal ideation (β = 0.04, 95% CI [0.02, 0.05]), and the relationship between baseline social anxiety symptoms and 2-year depressive symptoms (β = 0.06, 95% CI [0.03, 0.08]) after adjusting for age, sex, and other covariates.ResultsResults from multiple linear regression analyses indicated that baseline social anxiety symptoms were associated with 2-year suicidal ideation (β = 0.07, p < 0.05, 95% CI [0.02, 0.12]) and 2-year depressive symptoms (β = 0.08, p < 0.05, 95% CI [0.02, 0.13]), after controlling for baseline predicted variable. Furthermore, 1-year depressive symptoms significantly mediated the relationship between baseline social anxiety symptoms and 2-year suicidal ideation (β = 0.04, 95% CI [0.02, 0.05]), and the relationship between baseline social anxiety symptoms and 2-year depressive symptoms (β = 0.06, 95% CI [0.03, 0.08]) after adjusting for age, sex, and other covariates.We found evidence that baseline social anxiety symptoms were associated with 2-year suicidal ideation and 2-year depressive symptoms via 1-year depressive symptoms in non-clinical adolescents. These results may have important implications for targeted psychological interventions.ConclusionsWe found evidence that baseline social anxiety symptoms were associated with 2-year suicidal ideation and 2-year depressive symptoms via 1-year depressive symptoms in non-clinical adolescents. These results may have important implications for targeted psychological interventions.
Social anxiety disorder typically emerges in adolescence and its symptoms often co-occur with depression and suicidal ideation. It is important to understand whether social anxiety symptoms precede depression and suicidal ideation in youth. This study aimed to investigate the temporal associations between baseline social anxiety and later suicidal ideation and depressive symptoms in a community youth sample. The Wellcome Trust NSPN (Neuroscience in Psychiatry Network) study recruited 2397 youth aged 14-24 in the United Kingdom to participate in a prospective observational study. Participants were assessed for symptoms of social anxiety, generalised anxiety, depression and suicidal ideation at baseline, 1-year follow-up, and 2-year follow-up. We conducted multiple linear regression analyses and mediation analyses to examine whether baseline social anxiety was associated with 2-year suicidal ideation and depressive symptoms (excluding suicide-related items), and whether these associations were mediated by 1-year depressive symptoms. The study was preregistered on the Open Science Framework. Results from multiple linear regression analyses indicated that baseline social anxiety symptoms were associated with 2-year suicidal ideation (  = 0.07,  < 0.05, 95% CI [0.02, 0.12]) and 2-year depressive symptoms (  = 0.08,  < 0.05, 95% CI [0.02, 0.13]), after controlling for baseline predicted variable. Furthermore, 1-year depressive symptoms significantly mediated the relationship between baseline social anxiety symptoms and 2-year suicidal ideation (  = 0.04, 95% CI [0.02, 0.05]), and the relationship between baseline social anxiety symptoms and 2-year depressive symptoms (  = 0.06, 95% CI [0.03, 0.08]) after adjusting for age, sex, and other covariates. We found evidence that baseline social anxiety symptoms were associated with 2-year suicidal ideation and 2-year depressive symptoms via 1-year depressive symptoms in non-clinical adolescents. These results may have important implications for targeted psychological interventions.
Background Social anxiety disorder typically emerges in adolescence and its symptoms often co‐occur with depression and suicidal ideation. It is important to understand whether social anxiety symptoms precede depression and suicidal ideation in youth. This study aimed to investigate the temporal associations between baseline social anxiety and later suicidal ideation and depressive symptoms in a community youth sample. Methods The Wellcome Trust NSPN (Neuroscience in Psychiatry Network) study recruited 2397 youth aged 14–24 in the United Kingdom to participate in a prospective observational study. Participants were assessed for symptoms of social anxiety, generalised anxiety, depression and suicidal ideation at baseline, 1‐year follow‐up, and 2‐year follow‐up. We conducted multiple linear regression analyses and mediation analyses to examine whether baseline social anxiety was associated with 2‐year suicidal ideation and depressive symptoms (excluding suicide‐related items), and whether these associations were mediated by 1‐year depressive symptoms. The study was preregistered on the Open Science Framework. Results Results from multiple linear regression analyses indicated that baseline social anxiety symptoms were associated with 2‐year suicidal ideation (β = 0.07, p < 0.05, 95% CI [0.02, 0.12]) and 2‐year depressive symptoms (β = 0.08, p < 0.05, 95% CI [0.02, 0.13]), after controlling for baseline predicted variable. Furthermore, 1‐year depressive symptoms significantly mediated the relationship between baseline social anxiety symptoms and 2‐year suicidal ideation (β = 0.04, 95% CI [0.02, 0.05]), and the relationship between baseline social anxiety symptoms and 2‐year depressive symptoms (β = 0.06, 95% CI [0.03, 0.08]) after adjusting for age, sex, and other covariates. Conclusions We found evidence that baseline social anxiety symptoms were associated with 2‐year suicidal ideation and 2‐year depressive symptoms via 1‐year depressive symptoms in non‐clinical adolescents. These results may have important implications for targeted psychological interventions.
Abstract Background Social anxiety disorder typically emerges in adolescence and its symptoms often co‐occur with depression and suicidal ideation. It is important to understand whether social anxiety symptoms precede depression and suicidal ideation in youth. This study aimed to investigate the temporal associations between baseline social anxiety and later suicidal ideation and depressive symptoms in a community youth sample. Methods The Wellcome Trust NSPN (Neuroscience in Psychiatry Network) study recruited 2397 youth aged 14–24 in the United Kingdom to participate in a prospective observational study. Participants were assessed for symptoms of social anxiety, generalised anxiety, depression and suicidal ideation at baseline, 1‐year follow‐up, and 2‐year follow‐up. We conducted multiple linear regression analyses and mediation analyses to examine whether baseline social anxiety was associated with 2‐year suicidal ideation and depressive symptoms (excluding suicide‐related items), and whether these associations were mediated by 1‐year depressive symptoms. The study was preregistered on the Open Science Framework. Results Results from multiple linear regression analyses indicated that baseline social anxiety symptoms were associated with 2‐year suicidal ideation (β = 0.07, p < 0.05, 95% CI [0.02, 0.12]) and 2‐year depressive symptoms (β = 0.08, p < 0.05, 95% CI [0.02, 0.13]), after controlling for baseline predicted variable. Furthermore, 1‐year depressive symptoms significantly mediated the relationship between baseline social anxiety symptoms and 2‐year suicidal ideation (β = 0.04, 95% CI [0.02, 0.05]), and the relationship between baseline social anxiety symptoms and 2‐year depressive symptoms (β = 0.06, 95% CI [0.03, 0.08]) after adjusting for age, sex, and other covariates. Conclusions We found evidence that baseline social anxiety symptoms were associated with 2‐year suicidal ideation and 2‐year depressive symptoms via 1‐year depressive symptoms in non‐clinical adolescents. These results may have important implications for targeted psychological interventions.
Author Stringaris, Argyris
Leigh, Eleanor
Chiu, Kenny
AuthorAffiliation 1 Department of Clinical Psychology and Psychological Therapies University of East Anglia Norwich UK
3 First Department of Psychiatry Aiginiteion Hospital National and Kapodistrian University of Athens Athens Greece
4 Department of Experimental Psychology University of Oxford Oxford UK
2 Divisions of Psychiatry and Psychology and Language Sciences University College London London UK
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Issue 1
Keywords adolescent
depression
social phobia
social anxiety
youth
suicide
Language English
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Snippet Background Social anxiety disorder typically emerges in adolescence and its symptoms often co‐occur with depression and suicidal ideation. It is important to...
Social anxiety disorder typically emerges in adolescence and its symptoms often co-occur with depression and suicidal ideation. It is important to understand...
Abstract Background Social anxiety disorder typically emerges in adolescence and its symptoms often co‐occur with depression and suicidal ideation. It is...
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StartPage e12249
SubjectTerms adolescent
depression
Original
social anxiety
social phobia
suicide
youth
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Title Social anxiety symptoms and their relationship with suicidal ideation and depressive symptoms in adolescents: A prospective study
URI https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fjcv2.12249
https://www.ncbi.nlm.nih.gov/pubmed/40059992
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