Should the world collaborate imminently to develop neglected live‐attenuated vaccines for COVID‐19?

• Published in: Journal of medical virology Vol. 94; no. 1; pp. 82 - 87
• Main Author: Chen, Ji‐Ming
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.01.2022; John Wiley and Sons Inc
• Subjects: Animal research; Clinical trials; Collaboration; COVID-19; COVID-19 - prevention & control; COVID-19 Vaccines - immunology; Drug Development; Humans; Mass Vaccination; Monoclonal antibodies; Oral administration; pandemic; policy; Review; Reviews; Safety; SARS-CoV-2 - immunology; SARS‐CoV‐2; Severe acute respiratory syndrome; Severe acute respiratory syndrome coronavirus 2; vaccine; Vaccines; Vaccines, Attenuated - immunology; Viral diseases; Virology; Virulence; virus; Viruses; COVID-19; SARS-CoV-2; vaccine; safety; pandemic; virus; policy

The rapid spread of the Delta variant suggests that SARS‐CoV‐2 will likely be rampant for months or years and could claim millions of more lives. All the known vaccines cannot well defeat SARS‐CoV‐2 due to their limited efficacy and production efficiency, except for the neglected live‐attenuated vac...