Potential of live pathogen vaccines for defeating the COVID‐19 pandemic: History and mechanism

• Published in: Journal of medical virology Vol. 92; no. 9; pp. 1469 - 1474
• Main Authors: Chen, Ji‐Wang, Chen, Ji‐Ming
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.09.2020; John Wiley and Sons Inc
• Subjects: Adenoviruses; Animal research; Animals; antiviral; Antiviral drugs; Clinical trials; Clinical Trials as Topic; coronavirus; Coronaviruses; COVID-19; COVID-19 - prevention & control; COVID-19 vaccines; COVID-19 Vaccines - therapeutic use; Economic impact; Experiments; Humans; Infectious diseases; Medicine; Military personnel; Morbidity; Occupational safety; pandemic; Pandemics; Pathogens; Respiration; Respiratory diseases; Review; Reviews; Safety; Severe acute respiratory syndrome; Smallpox; Strategy; vaccine; Vaccines; Vaccines, Attenuated - therapeutic use; Veterinary medicine; Viral diseases; Virology; Viruses; coronavirus; vaccine; pandemic; strategy; safety; antiviral

The whole world has entered a terrible crisis with a huge and increasing number of human deaths and economic losses in fighting the pandemic of COVID‐19 caused by the novel coronavirus termed SARS‐CoV‐2. The live pathogen vaccine (LPV) strategy, which originated in ancient China for fighting smallpo...