Ortho Evra ™/Evra ™ versus oral contraceptives: follicular development and ovulation in normal cycles and after an intentional dosing error

• Published in: Fertility and sterility Vol. 80; no. 1; pp. 34 - 42
• Main Authors: Pierson, Roger A, Archer, David F, Moreau, Michèle, Shangold, Gary A, Fisher, Alan C, Creasy, George W
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.07.2003; Elsevier Science
• Subjects: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Alesse; Biological and medical sciences; Contraceptive Agents, Female - administration & dosage; Contraceptive Agents, Female - pharmacology; Contraceptives, Oral, Combined - administration & dosage; Contraceptives, Oral, Combined - pharmacology; Contraceptives, Oral, Hormonal - administration & dosage; Contraceptives, Oral, Hormonal - pharmacology; Estradiol - blood; Estradiol Congeners - administration & dosage; Estradiol Congeners - pharmacology; ethinyl estradiol; Ethinyl Estradiol - administration & dosage; Ethinyl Estradiol - pharmacology; Ethisterone - analogs & derivatives; Evra; Female; Follicle Stimulating Hormone - blood; follicular development; Genital system. Reproduction; Humans; levonorgestrel; Luteinizing Hormone - blood; Medical sciences; Medication Errors; norelgestromin; norgestimate; Norgestrel - analogs & derivatives; Ortho Evra; Ortho Tri-Cyclen; Ovarian Follicle - diagnostic imaging; Ovarian Follicle - drug effects; Ovarian Follicle - physiology; Ovulation - drug effects; Ovulation - physiology; Oximes; Pharmacology. Drug treatments; Progesterone - blood; Triphasil; Ultrasonography; Ortho Tri-Cyclen; Evra; follicular development; ethinyl estradiol; norgestimate; Triphasil; Alesse; Ortho Evra; norelgestromin; levonorgestrel; Ethinylestradiol; Human; Toxicity; Levonorgestrel; Oral administration; Norgestimate; Normal; Ovulation; Biological activity; Ovary; Norelgestromin; Female genital system; Female; Contraceptive; Ovarian follicle; Patch; Comparative study

To compare the effects of the contraceptive patch to oral contraceptives (OCs) on follicular size and incidence of ovulation in normal cycles and after dosing errors. Randomized, open-label. Twelve centers. One hundred twenty-four ovulatory women. Subjects received either the patch (groups 1 and 2)...