Molecular typing of coagulase-negative staphylococci from blood cultures does not correlate with clinical criteria for true bacteremia

• Published in: The American journal of medicine Vol. 109; no. 9; pp. 697 - 704
• Main Authors: Seo, Susan K, Venkataraman, Lata, DeGirolami, Paola C, Samore, Matthew H
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 15.12.2000; Elsevier; Elsevier Sequoia S.A
• Subjects: Bacteremia - diagnosis; Bacteremia - drug therapy; Bacteremia - microbiology; Bacteria; Bacterial Typing Techniques - methods; Bacteriology; Biological and medical sciences; Blood; Blood - microbiology; Coagulase - metabolism; Diagnosis, Differential; DNA Primers; DNA, Bacterial - isolation & purification; Electrophoresis, Gel, Pulsed-Field; Female; General aspects; Humans; Infection pathogenesis; Infectious diseases; Male; Medical sciences; Middle Aged; Molecular biology; Odds Ratio; Polymerase Chain Reaction; Prospective Studies; Staphylococcal Infections - diagnosis; Staphylococcal Infections - drug therapy; Staphylococcus - drug effects; Staphylococcus - enzymology; Staphylococcus - genetics; Human; Bacteremia; Staphylococcus; Incidence; Infection; Polymerase chain reaction; Symptomatology; Pulsed field electrophoresis; Bacteriosis; Bacteria; Micrococcales; Micrococcaceae; Molecular biology; Blood culture; Biological contamination

PURPOSE: Determining whether a blood culture that contains coagulase-negative staphylococci represents bacteremia or contamination is a clinical dilemma. We compared molecular-typing results of coagulase-negative staphylococcal blood culture isolates with clinical criteria for true bacteremia. SUBJE...